Evidence map›Paper›PMID 41527206›Full record

ArticleAmerican journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics2026

Black EquaLity in OCD NeuroGenomics (BELONG): Study Protocol.

Iasha J Williams, Dalia Y Marquez, Kara E Lopez-Lengowski, Malini Bommiasamy, Ogechi Cynthia Onyeka, Slayton J Underwood, Juliana E Avery, Jacob Gluckman, Thariana Pichardo, Rhea Chandler and 10 more

Abstract read
In one paragraph

Article in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Iasha J WilliamsDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas, USA.ORCID 0009-0006-7616-4396
Dalia Y MarquezDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Kara E Lopez-LengowskiDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Malini BommiasamyDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Ogechi Cynthia OnyekaDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas, USA.
Slayton J UnderwoodDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Juliana E AveryDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas, USA.
Jacob GluckmanDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.ORCID 0000-0003-2506-7319
Thariana PichardoDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Rhea ChandlerDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Yulu BrownDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Katie MangenDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas, USA.
Emma Grace ChoplinDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Black EquaLity in OCD NeuroGenomics (BELONG) Study Team
Sonyia C RichardsonSchool of Social Work, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Joseph D BuxbaumDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Eric A StorchDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas, USA.
James J CrowleyDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0001-9051-1557
Sidney H HankersonDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Dorothy E GriceDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.ORCID 0000-0002-8833-2549

Funding

Phenotypic and genetic architecture of OCD in African AmericansR01MH136218 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI DOROTHY E GRICE, SIDNEY H HANKERSON · 2024 to 2026
$2.5M
NIMH NIH HHS 1R01MH136218-01NIMH NIH HHS 5R01MH136218-02NIMH NIH HHS R01 MH136218
6 · The paper itself

Abstract

Obsessive-compulsive disorder (OCD) is a chronic, serious psychiatric disorder that affects 2%-3% of the population and is associated with high personal and societal costs. Genetic factors are estimated to explain roughly half the risk of developing OCD, and genomic studies are just beginning to identify common and rare genetic variants mediating this risk. A major goal of genomic studies is to yield insights into the etiology of OCD and identify molecular targets for the development of novel therapeutics. However, the overwhelming majority of subjects in existing genetic studies are of European ancestry, limiting the generalizability of these findings. To address this gap in understanding, we established the Black EquaLity in OCD NeuroGenomics (BELONG) study (https://belongocd.com/). BELONG aims to collect DNA and clinical data from 1250 richly phenotyped OCD cases of African ancestry in a culturally sensitive manner. In addition, BELONG includes the collection of parental DNA samples for trio-based analyses and unrelated matched controls for case-control analysis. DNA samples will be sequenced using optimized approaches that will allow us to examine both rare and common genome-wide variation to identify OCD risk genes. We will also meta-analyze these data with other existing OCD genomic data. Overall, BELONG will increase the representation of Black Americans in OCD genetic research, which is necessary to generalize precision medicine discoveries in psychiatric genetics.

Indexed as

Black or African AmericanObsessive-Compulsive DisorderCase-Control StudiesGenetic Predisposition to DiseaseGenome-Wide Association StudyGenomicsHumansResearch DesignAfrican ancestryBlackexomegeneticgenomicobsessive‐compulsive disorderOCDtrio

Identifiers

PMID41527206
PMCPMC13333079

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.