ArticleClinical & translational immunology2026
Prolonged persistence of tissue-resident memory cells in the upper airway following SARS-CoV-2 infection and vaccination.
Article in Clinical & translational immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: Here, we characterised the diversity and persistence of immunological memory cells-particularly tissue-resident memory T (T Methods: Nasopharynx (NP) samples were obtained using brushing from HV and BR subjects. Immune cell populations were analysed using transcriptomic profiling and flow cytometry. Results: Transcriptomic profiling revealed that the NP of SARS-CoV-2-infected individuals exhibited distinctive signatures of lymphocyte-mediated immunity, underscoring its role as a key site for viral invasion and immune activation. Effector memory CD4+ and CD8+ T (T Conclusion: Our findings identify the nasopharynx as a key site of long-lived immunological memory, marked by persistent T
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