Evidence map›Paper›PMID 41527582›Full record

ArticleHealth science reports2026

Incidence, Associated Risk Factors, and Outcomes of Postoperative Anxiety in Elderly: A Retrospective Observational Study.

Hao Guo, Li-Heng Li, Xiao-Hong Lv, Fei Xiao, Yu-Bo Xie

Abstract read
In one paragraph

Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hao GuoDepartment of Anesthesiology, Renmin Hospital Hubei University of Medicine Shiyan Hubei China.ORCID https://orcid.org/0000-0002-6547-5686
Li-Heng LiDepartment of Anesthesiology The First Affiliated Hospital of Guangxi Medical University Nanning Guangxi China.
Xiao-Hong LvDepartment of Anesthesiology, Shanxi Province Cancer Hospital, Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences Cancer Hospital Affiliated to Shanxi Medical University Taiyuan Shanxi China.
Fei XiaoDepartment of Anesthesiology, Beijing Anzhen Hospital Capital Medical University Beijing China.
Yu-Bo XieDepartment of Anesthesiology, Renmin Hospital Hubei University of Medicine Shiyan Hubei China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Postoperative anxiety (POA) is a frequently underrecognized complication in elderly surgical patients, with potential impacts on recovery and long-term mental health. This study aimed to investigate the incidence of POA, identify associated risk factors, and evaluate its short-term consequences in elderly individuals undergoing surgery. Methods: A retrospective observational study was conducted among patients aged 65 years and older who underwent elective surgery under general anesthesia between May 2020 and March 2021. Anxiety was measured using the Generalized Anxiety Disorder-7 (GAD-7) scale at baseline and during the first 7 days postoperatively. Postoperative pain, sleep quality, and other clinical outcomes were evaluated. Multivariable logistic regression identified independent risk factors for POA, and subgroup analyses were performed based on gender, frailty status, and surgery type. Missing data were handled using multiple imputation. Results: Among 308 eligible patients, 51.9% developed POA within 7 days post-surgery. The highest incidence occurred after orthopedic (64.6%) and urologic (60%) procedures. POA was significantly associated with worse postoperative pain (higher NRS scores, increased use of rescue analgesia) and poorer sleep quality on postoperative days 1-3. Multivariable analysis revealed that preoperative anxiety (OR, 3.60; 95% CI, 1.76-7.40) and preoperative sleep disturbance (OR, 3.34; 95% CI, 1.82-6.13) were identified as independent risk factors of POA. Anxiety at 30 and 90 days after surgery was significantly increased compared with those without POA (26% vs 15% and 22% vs 12%, respectively). Conclusion: POA is prevalent in elderly surgical patients and is associated with worse early postoperative outcomes. Screening for anxiety and sleep disturbances before surgery may help identify high-risk individuals. Early psychological or sleep-focused interventions could improve recovery and prevent persistent anxiety symptoms.

Indexed as

anxietyelderlygeneral anesthesiapainsleep quality

Identifiers

PMID41527582
PMCPMC12790690

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.