Evidence map›Paper›PMID 41528578›Full record

ReviewCurrent psychiatry reports2026

Sex Differences in Schizophrenia Across the Reproductive Lifespan.

Alexandre González-Rodríguez, Mentxu Natividad, Lorena Marín, María Emilia Chávez, Ariadna Balagué, Jennipher Paola Paolini San Miguel, José Antonio Monreal

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current psychiatry reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexandre González-RodríguezDepartment of Mental Health, Mutua Terrassa University Hospital, University of Barcelona (UB), CIBERSAM, 5, Doctor Robert Street, 08221, Terrassa, Spain. alexandregonzalez@mutuaterrassa.cat.
Mentxu NatividadDepartment of Mental Health, Mutua Terrassa University Hospital, University of Barcelona (UB), 08221, Terrassa, Spain.
Lorena MarínDepartment of Mental Health, Mutua Terrassa University Hospital, University of Barcelona (UB), 08221, Terrassa, Spain.
María Emilia ChávezDepartment of Mental Health, Mutua Terrassa University Hospital, University of Barcelona (UB), 08221, Terrassa, Spain.
Ariadna BalaguéDepartment of Mental Health, Mutua Terrassa University Hospital, University of Barcelona (UB), 08221, Terrassa, Spain.
Jennipher Paola Paolini San MiguelDepartment of Mental Health, Mutua Terrassa University Hospital, University of Barcelona (UB), 08221, Terrassa, Spain.
José Antonio MonrealDepartment of Mental Health, Mutua Terrassa University Hospital, University of Barcelona (UB), CIBERSAM, 5, Doctor Robert Street, 08221, Terrassa, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewA number of sex differences have been reported in people with schizophrenia in terms of epidemiological data and clinical and social needs. RECENT

findingsThis review examines recent evidence on sex differences in clinical outcomes, medical comorbidities and social risk factors in schizophrenia. Sex-specific personality traits and the effects of childhood maltreatment are relevant in schizophrenia. Insomnia is more common in women and is associated with depressive symptoms and cognitive impairment. Differences in antipsychotic dose requirements, risk of hospitalization and adverse events between men and women with schizophrenia have been reported and vary with age. The association between negative symptoms and 10-year cardiovascular risk are more common in men. Hyperglycaemia and dyslipidaemia are potential targets for sex stratification in the treatment of schizophrenia. Living without a spouse is associated with an increased risk of schizophrenia, which is higher in men than in women. Loneliness and social isolation are positively associated with clinical symptoms in men. The mental, physical and social needs of men and women with schizophrenia differ. This should be recognised when planning sex-specific programmes for psychosis.

Indexed as

SchizophreniaSchizophrenic PsychologySex CharacteristicsComorbidityFemaleHumansMaleRisk FactorsSex FactorsMental healthPhysical healthPsychosisSchizophreniaSexSocial risk

Identifiers

PMID41528578

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.