Evidence map›Paper›PMID 41528657›Full record

ReviewWorld journal of microbiology & biotechnology2026

Recent advances in microbial production of odd-chain fatty acids.

Rudolphus Antonius Timmers, Marta de Vicente, Aurora Rosa-Masegosa, Elvira Romero, Elia Tomás-Pejó, Cristina González-Fernández

Abstract readReview
In one paragraph

Review in World journal of microbiology & biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rudolphus Antonius TimmersCARTIF Technology Centre-Area of Circular Economy, Av. Francisco Vallés, 4, 47151, Boecillo, Valladolid, Spain.
Marta de VicenteBiotechnological Processes Unit, IMDEA Energy, Madrid, Móstoles, 28935, Spain.
Aurora Rosa-MasegosaDepartment of Chemical Engineering and Environmental Technology, School of Industrial Engineering, University of Valladolid, Dr. Mergelina, Valladolid, 47011, Spain.
Elvira RomeroBiotechnological Processes Unit, IMDEA Energy, Madrid, Móstoles, 28935, Spain.
Elia Tomás-PejóBiotechnological Processes Unit, IMDEA Energy, Madrid, Móstoles, 28935, Spain.
Cristina González-FernándezDepartment of Chemical Engineering and Environmental Technology, School of Industrial Engineering, University of Valladolid, Dr. Mergelina, Valladolid, 47011, Spain. cgonfer@uva.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The production of odd-chain fatty acids (OCFAs) is gaining increasing importance due to their diverse applications in food, chemical, and biofuel industries. These fatty acids, which are relatively rare in nature, can be produced from renewable carbon sources through microbial fermentation processes. This review covers the significance of OCFAs in the market and their occurrence, followed by a detailed exploration of their production in mixed and single strain cultures. Specifically, the anaerobic fermentation (AF) conditions and feedstocks used to produce short OCFAs (SOCFAs), such as propionic, valeric, and heptanoic acids are discussed. Additionally, the production of long OCFAs (LOCFAs) by single strains is focusing on yeast, bacteria, and microalgae. Novel approaches for LOCFAs generation from waste carbon sources are also reviewed. This work delves both into the manipulation of microbial communities covering bioaugmentation and process optimization for bioenrichment in open mixed cultures and genetic manipulation in single-strain systems. Finally, the potential for scalable and sustainable production of OCFAs through microbial processes is discussed, as well as the technological advances needed to optimize these pathways.

Indexed as

BacteriaFatty AcidsAnaerobiosisBiofuelsCarbonFermentationIndustrial MicrobiologyMetabolic EngineeringMicroalgaeYeastsBiofuelsCarbonFatty AcidsGenetic engineeringHeptanoic acidMicrobial fermentationOdd chain fatty acidsPentadecanoic acid and heptadecanoic acidPentanoic acidPropionic acid

Identifiers

PMID41528657
PMCPMC12799634

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.