Evidence mapPaperPMID 41529919Full record

SynthesisThe Journal of international medical research2026

The prognostic value of circulating soluble ST2 in patients with chronic heart failure.

Yue Zhang, Yunhong Liu, Yuanxia Yang, Lei Peng, Pengyu Zhong, Xiaoxin Jiang

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yue ZhangDepartment of Clinical Laboratory, People's Hospital of Longhua, Shenzhen, China.
Yunhong LiuDepartment of Clinical Laboratory, People's Hospital of Longhua, Shenzhen, China.
Yuanxia YangDepartment of Pharmacy, People's Hospital of Longhua, Shenzhen, China.
Lei PengDepartment of Urology, South China Hospital, Medical School, Shenzhen University, China.
Pengyu ZhongDepartment of Cardiology, Nanchong Central Hospital (Nanchong Hospital of Beijing Anzhen Hospital/The Second Clinical College of North Sichuan Medical College), China.
Xiaoxin JiangDepartment of Clinical Laboratory, People's Hospital of Longhua, Shenzhen, China.ORCID 0009-0006-6756-8380

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveThe purpose of this study was to assess whether circulating soluble ST2 independently predicts prognosis in patients with chronic heart failure.MethodsThis study was registered with the International Prospective Register of Systematic Reviews (PROSPERO) under the unique registration number CRD42023489018. Two researchers systematically searched PubMed, Embase, and Web of Science for all studies published up to 1 September 2024. To evaluate the quality of the study, the Newcastle-Ottawa Scale was used; Review Manager software was used for statistical analysis and construction of forest plots.ResultsThe final analysis comprised 17 studies in total. This meta-analysis demonstrated that a high soluble ST2 level was a predictor of poor all-cause mortality (hazard ratio: 1.03, 95% confidence interval: 1.02-1.04,

Indexed as

Heart FailureInterleukin-1 Receptor-Like 1 ProteinBiomarkersChronic DiseaseFemaleHumansMalePrognosisBiomarkersIL1RL1 protein, humanInterleukin-1 Receptor-Like 1 ProteinbiomarkerHeart failureprognosissoluble ST2soluble suppressor of tumorigenic protein-2

Identifiers

PMID41529919
PMCPMC12799978

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.