Evidence map›Paper›PMID 41530471›Full record

ArticleNeurosurgical review2026

Comparative outcomes of microsurgical and endovascular treatment for ruptured and unruptured anterior communicating artery aneurysms.

Bekir Can Kendirlioglu, Umid Sulaimanov, Ufuk Erginoglu, Selin Bozdag, Franco Patricio Vera Figueroa, Umut Tan Sevgi, Burcu Kok Kendirlioglu, Cagdas Ataoglu, Abdullah Keles, Abdurrahman Aycan and 4 more

Abstract readComparative Study
In one paragraph

Article in Neurosurgical review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Bekir Can KendirliogluDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, CSC K4/822, 600 Highland Avenue, Madison, WI, 53792, USA.
Umid SulaimanovDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, CSC K4/822, 600 Highland Avenue, Madison, WI, 53792, USA.
Ufuk ErginogluDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, CSC K4/822, 600 Highland Avenue, Madison, WI, 53792, USA.
Selin BozdagDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, CSC K4/822, 600 Highland Avenue, Madison, WI, 53792, USA.
Franco Patricio Vera FigueroaDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, CSC K4/822, 600 Highland Avenue, Madison, WI, 53792, USA.
Umut Tan SevgiDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, CSC K4/822, 600 Highland Avenue, Madison, WI, 53792, USA.
Burcu Kok KendirliogluDepartment of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, 55905, USA.
Cagdas AtaogluDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, CSC K4/822, 600 Highland Avenue, Madison, WI, 53792, USA.
Abdullah KelesDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, CSC K4/822, 600 Highland Avenue, Madison, WI, 53792, USA.
Abdurrahman AycanDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, CSC K4/822, 600 Highland Avenue, Madison, WI, 53792, USA.
Miner RossDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, CSC K4/822, 600 Highland Avenue, Madison, WI, 53792, USA.
Laura Stone McGuireDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, CSC K4/822, 600 Highland Avenue, Madison, WI, 53792, USA.
Azam Syed AhmedDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, CSC K4/822, 600 Highland Avenue, Madison, WI, 53792, USA.
Mustafa K BaskayaDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, CSC K4/822, 600 Highland Avenue, Madison, WI, 53792, USA. baskaya@neurosurgery.wisc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anterior communicating artery (AComA) aneurysms remain challenging because of their complex anatomy, rupture risk, and proximity to vital structures. This study compared the long-term durability, retreatment rates, complications, and outcomes of microsurgical clipping and endovascular treatment. This retrospective study included 313 patients (≥ 18 years) with ruptured or unruptured AComA aneurysms treated at a single center (2006-2024). Patients were categorized by treatment modality into two groups: (1) Microsurgical clipping and (2) Endovascular treatment. Primary outcomes included aneurysm occlusion status, retreatment, and functional recovery, measured by the Glasgow Outcome Scale and the modified Rankin Scale. Of the 313 patients, 166 (53.0%) underwent microsurgical clipping, and 147 (47.0%) received endovascular treatment. Complete occlusion was achieved in 98.2% of the microsurgical group compared to 38.1% in the endovascular group (p < 0.001). Retreatment was required for 15.6% of endovascular patients (excluding planned two-stage procedures), while no retreatments occurred for the microsurgical group (p < 0.001). There were no statistically significant differences in functional outcomes between treatment groups at discharge and follow-up. Mean aneurysm size was smaller for ruptured aneurysms (5.82 mm) than unruptured ones (6.80 mm; p = 0.020), and diabetes mellitus was more prevalent in the unruptured group (27.5% vs. 8.1%; p < 0.001). Microsurgical clipping provided significantly higher rates of complete occlusion and lower retreatment rates compared to endovascular coiling, with equivalent functional outcomes. These findings support the continued role of microsurgery for treating AComA aneurysms, particularly in patients requiring durable occlusion and less intensive long-term surveillance, although differences in rupture status between the treatment groups should be considered when interpreting these results.

Indexed as

Aneurysm, RupturedEndovascular ProceduresIntracranial AneurysmMicrosurgeryNeurosurgical ProceduresAdultAgedAnterior Cerebral ArteryFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeAneurysm occlusionAnterior communicating arteryEndovascular coilingMicrosurgical clippingSubarachnoid hemorrhage

Identifiers

PMID41530471
PMCPMC12799692

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.