Evidence map›Paper›PMID 41531191›Full record

ArticleBritish journal of clinical pharmacology2026

Trust first, concerns second: An international vignette study of older adults' preferences towards deprescribing statins.

Sarah E Vordenberg, Noelia Dulo, Carissa Bonner, Eliza Ferguson, Vincent D Marshall, Kristie Rebecca Weir

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in British journal of clinical pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sarah E VordenbergCollege of Pharmacy, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0002-9828-9759
Noelia DuloCollege of Pharmacy, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0009-0004-5273-2884
Carissa BonnerFaculty of Medicine and Health, Sydney School of Public Health, Leeder Centre for Health Policy, Economics, and Data, University of Sydney, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-4797-6460
Eliza FergusonFaculty of Medicine and Health, Sydney School of Public Health, University of Sydney, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-8154-2500
Vincent D MarshallCollege of Pharmacy, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0002-2594-7407
Kristie Rebecca WeirFaculty of Medicine and Health, Sydney School of Public Health, Leeder Centre for Health Policy, Economics, and Data, University of Sydney, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-9507-5050

Funding

U.S. Deprescribing Research NetworkR24AG064025 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI BOYD, CYNTHIA MELINDA, STEINMAN, MICHAEL A. · 2019 to 2023
$9.9M
Australian National Health and Medical Research Council Investigator Grant 2017295NIA NIH HHS R24AG064025Swiss Government Excellence ScholarshipSwiss National Science Foundation
6 · The paper itself

Abstract

This study investigated the attitudes and beliefs of older adults towards deprescribing statins in Australia, the United Kingdom and the United States, using an online, vignette-based study. Presented with a hypothetical scenario in which a general practitioner advised stopping simvastatin, participants rated their level of agreement and explained their rationale. Analysis was conducted incorporating the Patient Deprescribing Typology (PDT), which asks participants to share medication-related learning style, beliefs about importance, decision-making preferences and attitudes towards deprescribing. The findings correlated with participants' personal experiences with statins and their willingness to deprescribe in the scenario. The results highlight the importance of adapting deprescribing decisions to patients' beliefs and backgrounds to support shared decision-making. Future research is needed to assess whether typology-based screening tools can improve patient-centred deprescribing conversations in clinical practice.

Indexed as

DeprescriptionsHydroxymethylglutaryl-CoA Reductase InhibitorsPatient PreferenceTrustAgedAged, 80 and overAustraliaFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedPhysician-Patient RelationsSimvastatinSurveys and QuestionnairesUnited KingdomHydroxymethylglutaryl-CoA Reductase InhibitorsSimvastatincontent analysisdeprescribinginternationalmedicinesurvey

Identifiers

PMID41531191
PMCPMC13122286

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.