ArticleBioactive materials2026
Anisotropic mechanotransductive tissue constructs
Article in Bioactive materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Engineering aligned musculoskeletal and cardiac tissues remains a key challenge due to the lack of mechanical cues in conventional bioinks. Here, we present a synergistic strategy combining fiber-reinforced collagen bioinks with a brush-assisted bioprinting (BAB) process to fabricate highly organized, functional tissue constructs. The bioink incorporates straight and coiled poly(ε-caprolactone) (PCL) microfibers to deliver spatially defined biophysical guidance, while the BAB process applies directional and homogeneous shear stress to align both fibers and cells during printing. This integrated approach enhances cytoskeletal organization and activates mechanosensitive pathways, including
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