Evidence map›Paper›PMID 41532841›Full record

ArticleChemistry & biodiversity2026

Naphtho-γ-pyrones From Aspergillus foetidus, an Endophytic Fungus Isolated From Gardenia jasminoides J. Ellis.

Yi-Nong Wang, Li Zhu, Jia-Qi Liu, Liang Deng, Le Cai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yi-Nong WangSchool of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, P. R. China.
Li ZhuKey Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Characteristic Plant Extraction Laboratory, Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming, P. R. China.
Jia-Qi LiuSchool of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, P. R. China.
Liang DengSchool of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, P. R. China.
Le CaiKey Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Characteristic Plant Extraction Laboratory, Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming, P. R. China.ORCID https://orcid.org/0000-0003-0970-4920

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new naphtho-γ-pyrone dimer, asperforone A (1), along with thirteen known compounds, was isolated from the endophytic fungus Aspergillus foetidus of Gardenia jasminoides J. Ellis. Their structures were elucidated through comprehensive spectroscopic analysis and by comparison with literature data. Aspernigrin A (11) showed notable acetylcholinesterase inhibitory activity (46.98% at 50 µM), while asperforone A (1) and asperpyrone D (9) exhibited antimicrobial activity against Plectosphaerella cucumerina (minimum inhibitory concentration = 32 µg/mL). This study extends the chemical profile of A. foetidus and underscores its potential for bioactive metabolite discovery.

Indexed as

AspergillusCholinesterase InhibitorsGardeniaNaphthalenesPyronesAcetylcholinesteraseMicrobial Sensitivity TestsMolecular ConformationMolecular StructureAcetylcholinesteraseCholinesterase InhibitorsNaphthalenesPyronesAspergillus foetidusbiological activitynatural products

Identifiers

PMID41532841
PMCPMC13420201

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.