ArticleJournal of magnetic resonance imaging : JMRI2026
Multiparametric MRI for Predicting Renal Function Deterioration and Chronic Kidney Disease Development in Patients Undergoing Nephrectomy for Renal Masses: A Pilot Study.
Article in Journal of magnetic resonance imaging : JMRI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Kidney MRI Texture Analysis-A Universal Assessment of Kidney State and Function?Journal of clinical medicine · 2026Article
- Transition from acute kidney injury to chronic kidney disease: molecular mechanisms and therapeutic interventions.Molecular biomedicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
Abstract
backgroundPatients with solid renal masses (SRMs) are at risk of chronic kidney disease (CKD) after surgical resection without a reliable pre-operative predictor. PURPOSE: To investigate whether pre-operative multiparametric MRI (mpMRI) can predict CKD development and progression to stage 3 CKD. STUDY TYPE: Prospective. POPULATION: Forty-three participants (female = 13, mean age: 59 ± 12 years) undergoing nephrectomy for SRM. FIELD STRENGTH/SEQUENCE: 1.5 T, diffusion-weighted echo-planar imaging (DWI) using nine b-values (0-800 s/mm ASSESSMENT: A clinical CKD risk score was calculated from estimated glomerular filtration rate (eGFR), age, diabetes, and surgery (partial or radical nephrectomy). mpMRI parameters included cortical and medullary apparent diffusion coefficient (ADC), intravoxel incoherent motion (IVIM), tri-exponential diffusion (fast, medium, and slow), and spectral diffusion (vascular, tubule, and tissue) from DWI, native T STATISTICAL TESTS: Mann-Whitney U-test and Spearman's rank correlation coefficient (r). Diagnostic ability was determined by leave-one-out cross-validated logistic regression area-under-the-receiver-operator-curve (AUC) and diagnostic odds ratio (DOR) with p-value < 0.05 considered significant.
resultsThirty of 43 (67%) participants had normal baseline renal function (eGFR ≥ 60 mL/min/1.73 m DATA
conclusionPre-operative mpMRI predicted post-nephrectomy CKD development. A larger corticomedullary difference in ADC may indicate reduced functional reserve. EVIDENCE LEVEL: 1. TECHNICAL EFFICACY: Stage 2.
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Registered trials
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