Evidence map›Paper›PMID 41533304›Full record

ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2026

Hyperadrenergic postural tachycardia syndrome associated with augmented neurovascular transduction.

Surat Kulapatana, Luis E Okamoto, Stefano Rigo, Vasile Urechie, Thomas W Cayton, Ruijing E Han, Giris Jacob, William D Dupont, Raffaello Furlan, Italo Biaggioni and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Surat KulapatanaAutonomic Dysfunction Center, Department of Medicine, Division of Genetic Medicine and Clinical Pharmacology, Vanderbilt University Medical Center, 1161 21St Avenue South, Suite S3116 MCN, Nashville, TN, 37232-2600, USA.
Luis E OkamotoAutonomic Dysfunction Center, Department of Medicine, Division of Genetic Medicine and Clinical Pharmacology, Vanderbilt University Medical Center, 1161 21St Avenue South, Suite S3116 MCN, Nashville, TN, 37232-2600, USA.
Stefano RigoAutonomic Dysfunction Center, Department of Medicine, Division of Genetic Medicine and Clinical Pharmacology, Vanderbilt University Medical Center, 1161 21St Avenue South, Suite S3116 MCN, Nashville, TN, 37232-2600, USA.
Vasile UrechieAutonomic Dysfunction Center, Department of Medicine, Division of Genetic Medicine and Clinical Pharmacology, Vanderbilt University Medical Center, 1161 21St Avenue South, Suite S3116 MCN, Nashville, TN, 37232-2600, USA.
Thomas W CaytonAutonomic Dysfunction Center, Department of Medicine, Division of Genetic Medicine and Clinical Pharmacology, Vanderbilt University Medical Center, 1161 21St Avenue South, Suite S3116 MCN, Nashville, TN, 37232-2600, USA.
Ruijing E HanAutonomic Dysfunction Center, Department of Medicine, Division of Genetic Medicine and Clinical Pharmacology, Vanderbilt University Medical Center, 1161 21St Avenue South, Suite S3116 MCN, Nashville, TN, 37232-2600, USA.
Giris JacobDepartment of Internal Medicine F. and J. Recanati Autonomic Dysfunction Center, Tel Aviv Sourasky Medical Center, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
William D DupontDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, 37232‑2600, USA.
Raffaello FurlanHumanitas Clinical and Research Center-IRCCS, Via Alessandro Manzoni, 56, Rozzano, Italy.
Italo BiaggioniAutonomic Dysfunction Center, Department of Medicine, Division of Genetic Medicine and Clinical Pharmacology, Vanderbilt University Medical Center, 1161 21St Avenue South, Suite S3116 MCN, Nashville, TN, 37232-2600, USA.
André DiedrichAutonomic Dysfunction Center, Department of Medicine, Division of Genetic Medicine and Clinical Pharmacology, Vanderbilt University Medical Center, 1161 21St Avenue South, Suite S3116 MCN, Nashville, TN, 37232-2600, USA. andre.diedrich@vumc.org.ORCID http://orcid.org/0000-0001-5643-0294

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Autonomic Determinants of Postural Tachycardia SyndromeR01HL142583 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DIEDRICH, ANDRE · 2019 to 2022
$1.7M
NCATS NIH HHS 5UL1TR002243-03NCATS NIH HHS UL1 TR002243NHLBI NIH HHS R01 HL142583
6 · The paper itself

Abstract

purposeMuscle sympathetic nerve activity (MSNA) is valuable for managing postural tachycardia syndrome (POTS), but microneurography is clinically impractical. We investigated whether the Valsalva phase 2 diastolic blood pressure rise (DBP

methodsWe included 21 POTS women and 22 healthy women to perform Valsalva and microneurography. MSNA spike rate was obtained using stationary wavelet transformation. The DBP

resultsThe DBP

conclusionDBP

Indexed as

Blood PressurePostural Orthostatic Tachycardia SyndromeSympathetic Nervous SystemAdultFemaleHumansMuscle, SkeletalValsalva ManeuverYoung AdultHyperadrenergicMSNAPOTSSympatheticValsalva

Identifiers

PMID41533304
PMCPMC12931957

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.