ReviewBiological trace element research2026
Tellurium Nanoparticles in Biomedicine: Harnessing a "Jekyll and Hyde" Element for Therapy and Diagnosis.
Review in Biological trace element research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Tellurium, long considered a toxic element, now represents a unique platform for biomedical nanomaterials. Its fundamental paradox lies in its dual nature: depending on the form and dose, it exhibits both potent pro-oxidant activity against tumor cells and pathogens, and pronounced antioxidant properties. Tellurium nanoparticles (TeNPs) serve as a tool for managing this duality. This review systematizes modern methods of TeNPs synthesis, including laser ablation as a source of high-purity particles, and details the mechanisms of their biological action - from redox activity and modulation of calcium signaling to the targeted suppression of signaling pathways. Particular attention is paid to the application of TeNPs as antimicrobial and anticancer agents, and as modulators of central nervous system functions, where particle size determines the shift from neurotoxicity to neuroprotection. The analysis suggests the potential of TeNPs for creating new therapeutic platforms, although challenges related to their narrow therapeutic window and long-term safety remain.
Indexed as
Identifiers
41533327What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.