Evidence map›Paper›PMID 41533362›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2026

Novel assessment of postprandial metabolism reveals sex-specific metabolic flexibility and lipid remodeling following volumetric muscle loss.

Angela S Bruzina, Braydon A Crum, Leo A Goodman, Yan Er Ng, Rachel L Hawe, Jarrod A Call, Sarah M Greising

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Angela S BruzinaSchool of Kinesiology, University of Minnesota, Minneapolis, Minnesota, United States.ORCID 0000-0002-8258-952X
Braydon A CrumSchool of Kinesiology, University of Minnesota, Minneapolis, Minnesota, United States.
Leo A GoodmanSchool of Kinesiology, University of Minnesota, Minneapolis, Minnesota, United States.
Yan Er NgSchool of Kinesiology, University of Minnesota, Minneapolis, Minnesota, United States.
Rachel L HaweSchool of Kinesiology, University of Minnesota, Minneapolis, Minnesota, United States.ORCID 0000-0002-0915-7755
Jarrod A CallDepartment of Physiology and Pharmacology, University of Georgia, Athens, Georgia, United States.ORCID 0000-0002-1094-4940
Sarah M GreisingSchool of Kinesiology, University of Minnesota, Minneapolis, Minnesota, United States.ORCID 0000-0001-9285-4908

Funding

TRAINING PROGRAM IN MUSCLE RESEARCHT32AR007612 · UNIVERSITY OF MINNESOTA TWIN CITIES · 2001 to 2025
$1.5M
Pathological Foundations of Skeletal Muscle After Volumetric Muscle Loss and Targets For RehabilitationR01AR078903 · UNIVERSITY OF GEORGIA · 2025 to 2025
$442k
Age, Injury, and the Neuromuscular JunctionK02AG081488 · UNIVERSITY OF MINNESOTA · 2025 to 2025
$154k
HHS | National Institutes of Health (NIH) K02-AG081488HHS | National Institutes of Health (NIH) R01-AR078903HHS | National Institutes of Health (NIH) T32-AR007612NIAMS NIH HHS R01 AR078903NIAMS NIH HHS T32 AR007612NIA NIH HHS K02 AG081488
6 · The paper itself

Abstract

Localized skeletal muscle injury [e.g., volumetric muscle loss (VML)] can disrupt diurnal metabolic flexibility. However, it remains unclear how the evaluation of whole body metabolism and physical activity following a prandial stimuli may reveal differences in metabolic flexibility between injured and uninjured states. This study aimed to develop a novel tool to examine whole body metabolic impairments following VML injury, with consideration of lipid-related mechanisms. Adult C57BL/6J mice (

Indexed as

Energy MetabolismLipid MetabolismMuscle, SkeletalPostprandial PeriodAnimalsFemaleGlycerolMaleMiceMice, Inbred C57BLSex FactorsGlycerolfatty infiltrationintramuscular glycerol injectionin vivo muscle function

Identifiers

PMID41533362
PMCPMC12921476

What Socratic holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.