Evidence map›Paper›PMID 41533756›Full record

ReviewChemistry, an Asian journal2026

Early Transition Metal-Based Antitumor Complexes.

Xinyi Li, Xuanqi Fu, Xiaojie Pu, Siying Ju, Yufeng Zhao, Can Zhang, Jianhao Wang, Qibai Zhu, Lin Qiu, Yang Bai

Abstract readReview
In one paragraph

Review in Chemistry, an Asian journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xinyi LiSchool of Pharmacy, Changzhou University, Changzhou, P. R. China.
Xuanqi FuSchool of Life Sciences, Jiangsu Normal University, Xuzhou, P. R. China.
Xiaojie PuSchool of Pharmacy, Changzhou University, Changzhou, P. R. China.
Siying JuSchool of Pharmacy, Changzhou University, Changzhou, P. R. China.
Yufeng ZhaoSchool of Pharmacy, Changzhou University, Changzhou, P. R. China.
Can ZhangSchool of Pharmacy, Changzhou University, Changzhou, P. R. China.
Jianhao WangSchool of Pharmacy, Changzhou University, Changzhou, P. R. China.ORCID https://orcid.org/0000-0003-3133-6132
Qibai ZhuChangzhou Institute of Advanced Materials, Beijing University of Chemical Technology, Changzhou, P. R. China.
Lin QiuSchool of Pharmacy, Changzhou University, Changzhou, P. R. China.
Yang BaiSchool of Pharmacy, Changzhou University, Changzhou, P. R. China.ORCID https://orcid.org/0000-0002-4859-1167

Funding

National Natural Science Foundation of China 22207011
6 · The paper itself

Abstract

Cancer is a major disease that seriously threatens human health worldwide. The development of highly effective and low toxicity anticancer drugs has always been a research hotspot. Transition metal complexes, as antitumor drugs, offer multiple advantages, including the synergistic effect of targeting multiple sites, which reduces drug resistance, strong structural adjustability for optimizing the efficacy of the medicine, unique photodynamic/photothermal therapy capabilities, and the ability to integrate diagnosis and treatment. Early transition metals refer to the d-block metal elements from Group IIIB to Group VIIB in the periodic table. In recent years, antitumor complexes of early transition metals have received extensive attention due to their unique mechanisms of action and potential therapeutic effects. In this review, we summarize the latest advancements in the anticancer effects of metal complexes of Ti, V, Cr, Mn, Mo, Tc, and Re, which represent a new type of anticancer drug with multiple mechanisms, and are expected to provide more effective solutions for precise tumor treatment. With the deepening of research and the development of technology, early transition metal-based drugs may play a more important role in precision medicine.

Indexed as

Antineoplastic AgentsCoordination ComplexesNeoplasmsTransition ElementsHumansAntineoplastic AgentsCoordination ComplexesTransition Elementscancer therapeuticsearly transition metaltransition metal complex

Identifiers

PMID41533756
PMCPMC13394315

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.