Trial reportInvestigative ophthalmology & visual science2025
Retinal Neurovascular and Mitochondrial Function Signatures in Response to a 24-Week Yoga Intervention in Healthy Adults.
Trial report in Investigative ophthalmology & visual science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Reduced Retinal Perfusion With Preserved Microvascular Network Density in Early Alzheimer's Disease: A Multimodal Imaging Study.Translational vision science & technology · 2026Article
- Age-Related Neurovascular Dysfunction in the Retina and Potential Pathogenic Mechanisms.Investigative ophthalmology & visual science · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Purpose: To evaluate changes in retinal neurovascular and mitochondrial function after a 24-week yoga intervention in healthy older adults. Methods: Thirty participants (mean age 72 ± 6 years; 25 females, 5 males) were randomized to either a cue-based yoga program (n = 15) or traditional Hatha yoga (n = 15), with 60-minute sessions three times per week for 24 weeks. Retinal assessments were conducted at baseline and follow-up. Optical coherence tomography angiography (OCTA) was used to evaluate retinal structure and vessel density. Retinal blood flow was measured with the Retinal Function Imager, and mitochondrial function was assessed via macular flavoprotein fluorescence using the OcuMet Beacon. Results: Significant increases were observed in retinal blood flow (2.21 to 2.72 nL/s, P = 0.002), capillary function (0.12 to 0.14 nL/s/mm, P = 0.004), and tissue perfusion (1.91 to 2.38 nL/s/mm³, P = 0.004). Macular flavoprotein fluorescence decreased (31.7 to 30.1 gsu, P = 0.041), suggesting improved mitochondrial function. No significant changes were found in vessel density, vessel length density, foveal avascular zone area, choriocapillaris density, or total retinal thickness. Between-group differences were mostly nonsignificant, except for baseline and change values in choriocapillaris density and change values in retinal thickness (P < 0.05). Conclusions: A 24-week yoga intervention was associated with improved retinal blood flow, capillary efficiency, and tissue perfusion in healthy older adults, with indications of enhanced mitochondrial function. These findings suggest yoga may support retinal vascular and metabolic health during aging.
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Registered trials
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