Evidence map›Paper›PMID 41534831›Full record

ArticleThe Journal of biological chemistry2026

Hydrogen sulfide increases intracellular oxygen and inhibits the HIF response.

Joseph Brake, David A Hanna, Roshan Kumar, Qianni Peng, Aaron P Landry, Rashi Singhal, Eranthie Weerapana, Yatrik M Shah, Ruma Banerjee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Power and poison: The intersections of HThe Journal of biological chemistry · 2025
    Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Joseph BrakeDepartment of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, USA.
David A HannaDepartment of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, USA.
Roshan KumarDepartment of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, USA.
Qianni PengChemistry Department, Boston College, Chestnut Hill, Massachusetts, USA.
Aaron P LandryDepartment of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, USA.
Rashi SinghalDepartment of Molecular and Integrative Physiology, Ann Arbor, Michigan, USA.
Eranthie WeerapanaChemistry Department, Boston College, Chestnut Hill, Massachusetts, USA.
Yatrik M ShahDepartment of Molecular and Integrative Physiology, Ann Arbor, Michigan, USA; Department of Internal Medicine, Ann Arbor, Michigan, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.
Ruma BanerjeeDepartment of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, USA. Electronic address: rbanerje@umich.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxygen (O

Indexed as

Hydrogen SulfideHypoxia-Inducible Factor 1, alpha SubunitOxygenAnimalsCell HypoxiaHumansMiceQuinone ReductasesHydrogen SulfideHypoxia-Inducible Factor 1, alpha SubunitOxygenQuinone Reductasessulfide quinone reductasehydrogen sulfidehypoxiahypoxia-inducible factorhypoxia sensingoxygen metabolismsulfide quinone oxidoreductase

Identifiers

PMID41534831
PMCPMC12925153

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.