Evidence map›Paper›PMID 41535293›Full record

ArticleNPJ science of food2026

Optimizing muscle satellite cell sources for cultured meat: anatomical origin influences cellular properties and quality attributes.

Jeongeun Lee, Jinryong Park, Hyeonwoo La, Sanghoon Yoon, Kwonho Hong, Kwanseob Shim, Jeong Tae Do

Abstract read
In one paragraph

Article in NPJ science of food, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeongeun LeeSchool of Advanced Biotechnology, Konkuk University, Seoul, South Korea.
Jinryong ParkFood Processing Research Group, Korea Food Research Institute, Wanju, South Korea.
Hyeonwoo LaSchool of Advanced Biotechnology, Konkuk University, Seoul, South Korea.
Sanghoon YoonSchool of Advanced Biotechnology, Konkuk University, Seoul, South Korea.
Kwonho HongSchool of Advanced Biotechnology, Konkuk University, Seoul, South Korea.
Kwanseob ShimDepartment of Animal Biotechnology, Jeonbuk National University, Jeonju, South Korea. ksshim@jbnu.ac.kr.
Jeong Tae DoSchool of Advanced Biotechnology, Konkuk University, Seoul, South Korea. dojt@konkuk.ac.kr.

Funding

Korea Institute of Planning and Evaluation for Technology in Food, Agriculture and Forestry 322006-05-CG000National Research Foundation of Korea RS-2023-00208330 and RS-2024-00340604
6 · The paper itself

Abstract

Muscle satellite cells are integral to muscle growth and regeneration, making them critical for cultured meat production. However, the influence of anatomical origin on porcine muscle satellite cells (PMSCs) for food applications remains underexplored. Here, we compared PMSCs from neck, back, and leg muscles to identify the optimal cell source for cultured meat. Transcriptomic analysis showed region-specific gene expression, including differential HOX gene expression. Neck-derived PMSCs exhibited the highest proliferation, whereas back-derived PMSCs maintained the highest PAX7 and MYOD expressions during long-term culture. Back-derived PMSCs also exhibited superior differentiation, forming thicker myotubes with the highest fusion index, favoring fast-twitch fibers, and showing the highest protein content. In contrast, neck-derived PMSCs favored slow-twitch fibers and displayed the lowest protein content. These findings underscore the significance of cell source selection in optimizing muscle tissue engineering for scalable cultured meat production, contributing to the advancement of sustainable and alternative food technologies.

Identifiers

PMID41535293
PMCPMC12901286

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.