Evidence map›Paper›PMID 41535952›Full record

ReviewCritical care (London, England)2026

Multidisciplinary guidelines on renal replacement therapy in intensive care medicine.

Melanie Meersch-Dini, Mariam Abu-Tair, Matthias Bayer, Alexander Brinkmann, Romuald Bellmann, Frank Brunkhorst, Florian Custodis, David Czock, Otto Frey, Jan Galle and 14 more

Registry-linked trialAbstract readReview
In one paragraph

Review in Critical care (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07765030 (Evaluation of Clinical Characteristics and In-Hospital Outcomes of Critically Ill Patients Undergoing Hemodialysis or Continuous Venovenous Hemodiafiltration in the Emergency Department), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07765030 not yet recruitingnot on this map

Evaluation of Clinical Characteristics and In-Hospital Outcomes of Critically Ill Patients Undergoing Hemodialysis or Continuous Venovenous Hemodiafiltration in the Emergency Department

TypeobservationalSponsorAntalya Health Sciences UniversityRan2026 to 2026Enrolled150ConditionsAcute Kidney Injury, Kidney Failure, Acute, Kidney FailureArmsHemodialysis (HD), Continuous Venovenous Hemodiafiltration (CVVHDF)
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. CRRT and ECMO: one love or separate lives?Intensive care medicine · 2026
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Melanie Meersch-DiniDepartment of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany. meersch@uni-muenster.de.
Mariam Abu-TairDepartment of Nephrology and Diabetology, Evangelisches Klinikum Bethel, Bielefeld, Germany.
Matthias BayerAsklepios Klinik Lich GmbH, Lich, Germany.
Alexander BrinkmannDepartment of Anesthesia and Critical Care Medicine, General Hospital of Heidenheim, Heidenheim, Germany.
Romuald BellmannDivision of Medical Intensive Care and Emergency Medicine, Clinical Pharmacokinetics Unit, Department of Internal Medicine I, Medical University of Innsbruck, Innsbruck, Austria.
Frank BrunkhorstInstitute of Infectious Diseases and Infection Control, Jena University Hospital, Jena, Germany.
Florian CustodisDepartment of Internal Medicine II, Klinikum Saarbrücken, Saarbrücken, Germany.
David CzockInternal Medicine IX, Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, Heidelberg, Germany.
Otto FreyDepartment of Pharmacy, General Hospital of Heidenheim, Heidenheim, Germany.
Jan GalleMärkische Kliniken GmbH, Klinikum Lüdenscheid, Lüdenscheid, Germany.
Carsten HermesUniversity of Applied Sciences Hamburg, Hamburg, Germany.
Michael JoannidisDivision of Intensive Care and Emergency Medicine, Department of Internal Medicine, Medical University of Innsbruck, Innsbruck, Austria.
Stefan JohnDepartment of Internal Medicine, Klinikum Nürnberg, Nürnberg, Germany.
Achim JörresDepartment of Medicine I-Nephrology, Transplantation & Medical Intensive Care, Medical Center Cologne-Merheim, University Witten/Herdecke, Cologne, Germany.
Thomas KerzDepartment of Neurosurgery, University Medical Center Mainz, Mainz, Germany.
Detlef Kindgen-MillesDepartment of Anesthesiology, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.
Martin KoczorBundesverband Niere e.V, Mainz, Germany.
Rainer KramDepartment of Anesthesiology, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.
Martin KuhlmannDepartment of Internal Medicine - Nephrology, Vivantes Klinikum im Friedrichshain, Berlin, Germany.
Michael OppertDepartment of Emergency and Intensive Care Medicine, Klinikum Ernst von Bergmann Klinikum, Potsdam, Germany.
Georg SchlieperCenter for Nephrology, Hypertension and Metabolic Diseases, Hannover, Germany.
Michael SchmitzDepartment of Nephrology, Städtisches Klinikum Solingen, Solingen, Germany.
Alexander ZarbockDepartment of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany.
Carsten WillamDepartment of Nephrology and Hypertension, Friedrich-Alexander-University Erlangen-Nürnberg, University Hospital Erlangen, Erlangen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRenal replacement therapy (RRT) is frequently used in critically ill patients with acute kidney injury (AKI). Here, we provide guidelines for the management of RRT in critically ill patients on the intensive care unit (ICU).

methodsWe convened a systemic literature research and a Delphi process with a bi-national multidisciplinary consensus panel including 22 clinicians of 12 different German-speaking societies (Germany and Austria) with expertise in RRT. This structured guideline process was the basis for the evidence-based statements and recommendations.

resultsWe identified seven clinical areas needing guidance: (1) start, (2) modality (diffusion and convection), (3) continuous/ intermittent, (4) anticoagulation, (5) dose (6) pharmacotherapy, (7) stopping criteria. The consensus produced 73 statements and recommendations regarding key clinical areas, the most important 47 statements and recommendations are summarized in this overview.

conclusionsThis evidence-based bi-national guideline should provide physicians with guidance for delivering best practice to critically ill patients with a dialysis-dependent AKI.

Indexed as

Renal Replacement TherapyAcute Kidney InjuryAustriaCritical CareCritical IllnessDelphi TechniqueGermanyHumansIntensive Care UnitsPractice Guidelines as TopicAcute kidney injuryAdultsGuidelinesICUPharmacotherapyRenal replacement therapy

Identifiers

PMID41535952
PMCPMC12849416

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.