Evidence map›Paper›PMID 41535963›Full record

ArticleExperimental hematology & oncology2026

Gastric and upper gastrointestinal oncology: integrating breakthroughs from prevention to precision therapeutics.

JunLi Chen, JiLong Wang, LuLu Cai, Jian Li

Abstract readLetter
In one paragraph

Article in Experimental hematology & oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

JunLi ChenDepartment of Traditional Chinese Medicine, The Shapingba Hospital, Chongqing University, People's Hospital of Shapingba District, Chongqing, 400030, China.
JiLong WangDepartment of Traditional Chinese Medicine, The Shapingba Hospital, Chongqing University, People's Hospital of Shapingba District, Chongqing, 400030, China.
LuLu CaiDepartment of Pharmacy, Personalized Drug Research and Therapy Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, Sichuan, China.
Jian LiSchool of Bioscience and Technology, Chengdu Medical College, Chengdu, 610072, Sichuan, China. ianlly@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric and upper gastrointestinal (GI) oncology is at a point of transformation, with significant advances in each aspect of the disease continuum. Novel clinical tools and therapies, including randomized phase II and III trials, have provided new standards of care for patients, including preoperative chemoradiation for resectable gastric cancer and PD-L1 stratified immuno-chemotherapy in the metastatic setting. Also, many discoveries are co-evolving with newer methods, such as CAR-T therapy or reintroduced microbial undercover agents or burgeoning precision tools. However, obstacles remain, nursing the costs of CAR-T, the paradoxical survival benefit of PD-L1 P146R polymorphism, and other biological ineptitudes along with health system barriers. In this synthesis, we advocate for more closely integrated "bench-to-community" approaches to apply more effective combinations of health population prevention programs, biomarker-guided therapeutics, and omics profiling studies to accelerate and positively impact healthcare practices addressing biological or health system barriers.

Indexed as

BiomarkerGastric cancerImmunochemotherapyPrecision oncologySpatial multi-omicsTherapeutics strategies

Identifiers

PMID41535963
PMCPMC12805685

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.