Evidence map›Paper›PMID 41536046›Full record

ArticleRenal failure2025

Aucubin ameliorates diabetic kidney disease by restoring hGENCs autophagy through promoting phosphorylation of ATG4B protein.

Hong Wang, Lei Yang, Dishu Ao, Kai Yang, Songzhu Zou, Zhengjun Lin, Qi Liu, Kunming Wen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A macrophage-endothelial cell axis in kidney diseases.International urology and nephrology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hong WangDepartment of Nephrorheumatology, Soochow University Medical College, Suzhou, Jiangsu, China.
Lei YangDepartment of Nephrorheumatology, The Second Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Dishu AoDepartment of Microbiology, School of Basic Medical Sciences, Zunyi Medical University, Zunyi, Guizhou, China.
Kai YangDepartment of General Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Songzhu ZouDepartment of General Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Zhengjun LinDepartment of General Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Qi LiuDepartment of Nephrorheumatology, Soochow University Medical College, Suzhou, Jiangsu, China.
Kunming WenDepartment of Nephrorheumatology, Soochow University Medical College, Suzhou, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aucubin is a major component of

Indexed as

AutophagyAutophagy-Related ProteinsDiabetic NephropathiesEndothelial CellsIridoid GlucosidesAnimalsCysteine EndopeptidasesDiabetes Mellitus, ExperimentalDisease Models, AnimalGlucoseHumansKidney GlomerulusMaleMiceMice, Inbred C57BLPhosphorylationATG4B protein, humanAtg4b protein, mouseaucubinAutophagy-Related ProteinsCysteine EndopeptidasesGlucoseIridoid GlucosidesATG4BAucubinautophagydiabetic kidney diseaseglomerular endothelial cellsphosphorylation

Identifiers

PMID41536046
PMCPMC12810412

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.