Evidence map›Paper›PMID 41536812›Full record

ArticleMolecular therapy. Nucleic acids2026

Combining anti-gene γPNA with small molecules and RNA inhibitors: A strategy to enhance anti-tumor efficacy.

Sai Pallavi Pradeep, Brooke Elizabeth DiVasto, Peter M Glazer, Raman Bahal

Abstract read
In one paragraph

Article in Molecular therapy. Nucleic acids, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sai Pallavi PradeepDepartment of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269, USA.
Brooke Elizabeth DiVastoDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT 06269, USA.
Peter M GlazerDepartment of Therapeutic Radiology and Genetics, Yale University, New Haven, CT 06520, USA.
Raman BahalDepartment of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Targeting genomic DNA to silence oncogenes is a promising strategy for cancer therapy. Gamma peptide nucleic acid (γPNA) targeting

Indexed as

c-Myccombination therapyHDACiMT: Oligonucleotides: Therapies and ApplicationsMYC/MAX inhibitorspeptide nucleic acidsiRNAtranscription inhibitionγPNA

Identifiers

PMID41536812
PMCPMC12796863

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.