ArticleJournal of clinical and experimental hepatology
Screening for Malnutrition, Sarcopenia, and Physical Frailty Beyond One Year after Liver Transplantation.
Article in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
6 authors.
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Abstract
Background/Aims: Malnutrition, sarcopenia, and frailty negatively impact quality of life and increase mortality following liver transplantation (LT). However, long-term follow-up data remain limited. This study aimed primarily to assess the malnutrition risk at 1-, 2-, and 3-years post-LT. Secondary objectives included evaluating the sarcopenia and frailty risk, muscle function, physical activity, quality of life, and employment status at the same time points. Methods: This cross-sectional study included LT recipients with a history of cirrhosis, transplanted between January 2019 and December 2021. Each participant completed a single virtual meeting during which nutritional risk, sarcopenia, frailty risk, muscle function, physical activity, quality of life, employment status, and dietary intakes were assessed. Results: Sixty-six LT recipients (63.6% male) were included: cohort A (1-year post-LT, n = 25), cohort B (2 years post-LT, n = 14), and cohort C (3 years post-LT, n = 27). The prevalence of malnutrition (12.0%, 14.3%, and 11.1%), sarcopenia (16.0%, 28.6%, and 18.5%), and frailty risks (12.0%, 28.6%, and 18.5%) in cohorts A, B, and C, respectively, remained stable over time ( Conclusion: Up to 3 years after LT, patients were still at risk of malnutrition, sarcopenia, and frailty. The results of this study highlight the need for targeted interventions to improve outcomes and support long-term quality of life post-LT.
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