ArticleMaedica2025
Evaluation of Inflammatory Biomarkers in Post-COVID-19 Arthritis: a Cross-Sectional Study from Telangana, South India.
Article in Maedica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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14 authors.
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Abstract
Background: Long COVID, a post-COVID-19 syndrome, has been linked to various musculoskeletal manifestations, particularly arthritic symptoms. This study aimed to evaluate the inflammatory markers associated with long COVID in patients diagnosed with COVID arthritis. Methods: A cross-sectional prospective study was conducted in a tertiary care centre in Telangana, India, involving 139 PCR-confirmed COVID-19 patients diagnosed with arthritis. Eligible participants were COVID-free for one month to six months. Clinical histories, including severity of arthritis symptoms, levels of inflammatory markers (LDH, uric acid, serum ferritin, rheumatoid factor [RF] and CRP) and radiological investigations (radiographs and ultrasound) were recorded and analyzed. Follow-up assessments occurred at six months, with repeated measurements of inflammatory markers for statistical significance. Results: The predominant clinical presentations included joint aches, restricted movement, swelling, myalgia and fatigue, with 95% of subjects relying on over-the-counter analgesics. Notably, all measured inflammatory markers decreased over the six-month follow-up, with statistically significant reductions being observed in LDH, RF and CRP levels. Conclusion: COVID arthritis is a complication of long COVID that affects both men and women, with persistent elevation of inflammatory biomarkers. While levels decreased during the follow-up period, extended monitoring is necessary to determine the duration required for normalization. Further research is warranted to understand the long-term implications of these findings.
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