ReviewNEJM evidence2025
Pharmacologic Therapies for Type 2 Diabetes.
Review in NEJM evidence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Irisin upregulation as a contributory mechanism for the therapeutic benefits of SGLT-2 inhibitors.Pharmacology & therapeutics · 2026Review
- Potential of Triazines as Antidiabetic Agents-A Review of Structures and Pharmacological Activity.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Effects of QiShenYiQi dropping pills on gut dysbiosis and statin-associated muscle symptoms in ApoEFrontiers in cell and developmental biology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
AbstractType 2 diabetes (T2D) is a complex chronic disorder with an increasing prevalence. Treatment of T2D involves both lifestyle and pharmacologic interventions aimed at lowering blood glucose levels to help counteract the negative effects of long-term hyperglycemia. The range of pharmacologic treatments for T2D has grown substantially, with newer agents demonstrating not only glucose-lowering efficacy, but also reductions in long-term cardiometabolic complications. This review discusses the newest pharmacologic agents for the treatment of T2D and the evidence regarding their cardiometabolic benefits. We highlight key considerations for their use based on patient characteristics and clinical context. In addition, we discuss emerging pharmacologic therapies that target the underlying pathogenesis of T2D, underscoring ongoing advances in diabetes care.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.