ArticleNature communications2026
Genomic and physiological signatures of adaptation in pathogenic fungi.
Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Fungal DNA damage repair: from model to driver of virulence and AMR.Bioscience reports · 2026Review
- Winter Grazing in Vineyards Suppresses Pathogens and Promotes Grapevine Health.Plants (Basel, Switzerland) · 2026Article
- Genus-wide comparative genomics ofIMA fungus · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Emerging fungal pathogens have detrimental impacts on crops, animals, and humans. Despite the mounting threat of these emerging fungal pathogens, little is known about their transition from saprotrophic to pathogenic lifestyles. To gain insights into fungal lifestyle transitions, we study the Trichosporonales order, which includes both saprotrophic species and opportunistic human pathogens, as a system to reveal evolutionary adaptations leading to virulence in fungi. Here we use comparative genome analyses and experimental assays to demonstrate that the transition from saprotroph to opportunistic human pathogen is facilitated by adaptive translation. Codon optimization of metabolic genes grants these fungi the ability to quickly adapt to new environments. In this study, we link genomic data with fungal physiology, highlighting the role of adaptive translation in colonizing different environments and suggesting that gene translation optimization plays a critical role in fungal lifestyle evolution.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.