Evidence map›Paper›PMID 41540250›Full record

ArticleNPJ digital medicine2026

A guided chatbot-based psychological intervention for psychologically distressed older adolescents and young adults: a randomised clinical trial in Jordan.

Richard A Bryant, Anne M de Graaff, Rand Habashneh, Sarah Fanatseh, Dharani Keyan, Aemal Akhtar, Adnan Abualhaija, Muhannad Faroun, Ibrahim Said Aqel, Latefa Dardas and 5 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Richard A BryantSchool of Psychology, University of New South Wales, Sydney, NSW, Australia. r.bryant@unsw.edu.au.
Anne M de GraaffDepartment of Noncommunicable Diseases and Mental Health, World Health Organization, Geneva, Switzerland.
Rand HabashnehInstitute for Family Health, King Hussein Foundation, Amman, Jordan.
Sarah FanatsehInstitute for Family Health, King Hussein Foundation, Amman, Jordan.
Dharani KeyanSchool of Psychology, University of New South Wales, Sydney, NSW, Australia.
Aemal AkhtarDepartment of Noncommunicable Diseases and Mental Health, World Health Organization, Geneva, Switzerland.
Adnan AbualhaijaInstitute for Family Health, King Hussein Foundation, Amman, Jordan.
Muhannad FarounInstitute for Family Health, King Hussein Foundation, Amman, Jordan.
Ibrahim Said AqelInstitute for Family Health, King Hussein Foundation, Amman, Jordan.
Latefa DardasCommunity Health Nursing Department, School of Nursing, The University of Jordan, Amman, Jordan.
Hadeel AfarWorld Health Organization, Jordan Country Office, Amman, Jordan.
Chiara ServiliDepartment of Noncommunicable Diseases and Mental Health, World Health Organization, Geneva, Switzerland.
Dusan Hadzi-PavlovicSchool of Psychiatry, University of New South Wales, Sydney, NSW, Australia.
Mark van OmmerenDepartment of Noncommunicable Diseases and Mental Health, World Health Organization, Geneva, Switzerland.
Kenneth CarswellDepartment of Noncommunicable Diseases and Mental Health, World Health Organization, Geneva, Switzerland.

Funding

ELHRA Grant 44860World Health Organization 001
6 · The paper itself

Abstract

This randomised controlled trial compared a 10-session chatbot intervention with 5 weekly brief support calls (STARS) to enhanced usual care (EUC) in distressed young adults in Jordan (N = 344). Primary outcome was change in anxiety and depression severity assessed at baseline by the Hopkins Symptom Checklist (HSCL), 1-week posttreatment, and 3 months after treatment (primary outcome timepoint), as well as secondary outcome measures of psychological distress, personally identified problems, functional impairment, wellbeing and perceived agency. At the 3-month assessment, relative to EUC participants enrolled in STARS reported greater reductions of anxiety (effect size, 0.70) and depression (size, 0.61), as well as greater reductions in psychological distress, personally identified problems, functional impairment and greater improvement in wellbeing and sense of agency. Similar levels of efficacy were retained even for those with more severe symptom levels. This guided chatbot offers a scalable psychological intervention that can be implemented to increase access to evidence-based mental health care. Trial Registration: The trial was prospectively registered on ISRCTN on 02/11/2022 ( https://doi.org/10.1186/ISRCTN19217696 ).

Identifiers

PMID41540250
PMCPMC12820349

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.