Evidence mapPaperPMID 41540253Full record

Trial reportNature metabolism2026

The differential impact of three different NAD

Stefan Christen, Karine Redeuil, Laurence Goulet, Maria-Pilar Giner, Isabelle Breton, Riccardo Rota, Adrien Frézal, Atiye Nazari, Pieter Van den Abbeele, Jean-Philippe Godin and 2 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nature metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Article
  7. Whole-blood NADNature metabolism · 2026
    Article
  8. Nutrition Information Briefs - Niacin.Advances in nutrition (Bethesda, Md.) · 2026
    Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Stefan ChristenNestlé Research, Lausanne, Switzerland.
Karine RedeuilNestlé Research, Lausanne, Switzerland.
Laurence GouletNestlé Research, Lausanne, Switzerland.
Maria-Pilar GinerNestlé Research, Lausanne, Switzerland.ORCID http://orcid.org/0009-0004-3206-7119
Isabelle BretonNestlé Research, Lausanne, Switzerland.
Riccardo RotaNestlé Research, Lausanne, Switzerland.
Adrien FrézalNestlé Research, Lausanne, Switzerland.ORCID http://orcid.org/0009-0001-8668-1227
Atiye NazariNestlé Research, Lausanne, Switzerland.
Pieter Van den AbbeeleCryptobiotix, Ghent, Belgium.
Jean-Philippe GodinNestlé Research, Lausanne, Switzerland.
Sophie NuttenNestlé Research, Lausanne, Switzerland.ORCID http://orcid.org/0000-0003-0481-9286
Bernard CuenoudNestlé Health Science, Lausanne, Switzerland. Bernard.m.cuenoud@gmail.com.ORCID http://orcid.org/0000-0001-5120-1740

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nicotinamide adenine dinucleotide (NAD(H)) and its phosphorylated form NADP(H) are vitamin B

Indexed as

NADNiacinamideNicotinamide MononucleotideAdultDietary SupplementsFemaleHumansMaleMicrobiotaMiddle AgedNiacinPyridinium CompoundsYoung AdultNADNiacinNiacinamidenicotinamide-beta-ribosideNicotinamide MononucleotidePyridinium Compounds

Identifiers

PMID41540253
PMCPMC12855009

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.