Evidence map›Paper›PMID 41540788›Full record

Observational studyBrain and behavior2026

Monocyte-to-Albumin Ratio Predicts the Functional Outcome of Adults With Status Epilepticus: An Observational Study.

Jie Fu, Lilei Peng, Jinglun Li, Jun Liu, Shan Zeng

Abstract readObservational Study
In one paragraph

Observational study in Brain and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jie FuDepartment of Neurology, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.ORCID https://orcid.org/0000-0002-1388-8040
Lilei PengDepartment of Neurosurgery, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.ORCID https://orcid.org/0000-0002-1128-0066
Jinglun LiDepartment of Neurology, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.ORCID https://orcid.org/0009-0003-3494-1562
Jun LiuDepartment of Neurology, the Wangcang County People's Hospital, Guangyuan, Sichuan, China.ORCID https://orcid.org/0009-0008-8443-7010
Shan ZengDepartment of Neurosurgery, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.ORCID https://orcid.org/0009-0003-2494-1948

Funding

the Strategic Cooperation Project of Luzhou Municipal People's Government-Southwest Medical University 2024LZXNYDJ052the Youth Program of the Natural Science Foundation of Sichuan ProvinceYouth Program of the Natural Science Foundation of Sichuan Province 2025ZNSFSC1642
6 · The paper itself

Abstract

backgroundStatus epilepticus (SE) is a serious neuro-emergency that is often associated with unfavorable outcomes. It is known that inflammation is involved in the pathogenesis of SE, and various inflammatory markers have been suggested to be related to SE prognosis. Monocyte-to-albumin ratio (MAR), a novel biomarker of systemic inflammation, is derived from monocyte count and albumin levels. In this study, we sought to explore whether MAR could serve as a predictor of functional outcomes in SE.

methodsThis retrospective study collected the data of adult patients with SE. Functional outcomes of SE patients were evaluated by using the Modified Rankin Scale (mRS). Multivariable logistic regression analysis was performed to investigate the association of MAR with SE outcomes. Moreover, receiver operating characteristic (ROC) curve analysis was carried out to determine the optimal MAR threshold for predicting poor SE outcomes.

resultsThis study included 163 SE patients. Poor outcome at discharge was observed in 39.3% (64/163). Multivariate analysis showed that higher MAR at admission was independently related to unfavorable outcomes of SE patients (odds ratio: 1.092; 95% confidence interval, 1.023-1.166; p = 0.008). ROC curve analysis demonstrated that MAR could predict poor SE outcomes, with an area under the curve of 0.717 (95% CI: 0.638-0.795, p < 0.001). The optimal predictive cutoff point of MAR for poor SE outcomes was 13.78 (sensitivity 59.38%, specificity 73.74%).

conclusionHigher MAR at admission is closely correlated with an elevated risk of poor functional outcomes at discharge of SE patients. Our data suggest that MAR may be a promising and easily measurable marker for predicting short-term SE outcomes.

Indexed as

MonocytesSerum AlbuminStatus EpilepticusAdultAgedBiomarkersFemaleHumansInflammationMaleMiddle AgedPrognosisRetrospective StudiesROC CurveBiomarkersSerum Albumin

Identifiers

PMID41540788
PMCPMC12808917

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.