ArticleJAR life2026
Absolute and relative handgrip strength as indicators of cognitive impairment: Evidence from the Mexican cognitive aging study.
Article in JAR life, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Cross-cohort insights into the association of handgrip strength transitions and burdens with cardiovascular disease risk.SSM - population health · 2026Article
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Authors and funding
5 authors.
Funding
Abstract
Aim: Handgrip strength (HGS) is a simple, noninvasive measure that may help with the early detection and risk assessment of cognitive decline in middle-aged and older adults. This study aimed to explore the relationship between both absolute and relative measures of HGS and cognitive impairment in a nationally representative sample of Mexican adults aged 55 and older. Methods: This secondary cross-sectional study included 1870 participants (58.4% women; mean age = 68.1 ± 8.7 years) from the Mexican Cognitive Aging Study (Mex-Cog). Data from individuals aged ≥ 55 years included socioeconomic, lifestyle, anthropometric, and biomarker information. HGS was assessed using a dynamometer in absolute values (kg) and relative indices (HGS/height, HGS/height², HGS/weight, and HGS/BMI). Quartiles (Q) were created, with Q4 representing the highest performance. Cognitive impairment was defined as an MMSE score of < 24 points. Associations were examined using sex-stratified binary logistic regression adjusted for age, education level, and population density. Results: Women in the lowest quartile of absolute handgrip strength had significantly higher odds of cognitive impairment than those in the highest quartile (odds ratio [OR] = 2.24, 95% CI 1.04-4.80, Conclusions: Lower absolute and relative HGS values were strongly associated with a higher likelihood of cognitive impairment in Mexican adults. Due to its low cost, accessibility, and reproducibility, HGS may represent a practical biomarker for the early detection and tracking of cognitive decline, particularly in low-resource settings.
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Registered trials
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