Evidence map›Paper›PMID 41541199›Full record

ArticleRSC advances2026

Design and synthesis of new phosphazine and triazole derivatives for treatment of Alzheimer's disease: modulating ROS/JNK and Wnt/β-catenin signaling pathways.

Rania S Salah, Naglaa F El-Sayed, Marwa El-Hussieny, Shaimaa T Mansour, Mohamed Othman, Marwa A Fouad, Huda R M Rashdan, Ewies F Ewies, Heba S A Gharib, Ghada H Elsayed

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rania S SalahHormones Department, Medical Research and Clinical Studies Institute, National Research Centre 33 El-Bohouth St., Dokki 12622 Giza Egypt ghadanrc@yahoo.com gh.hamdi@nrc.sci.eg.ORCID https://orcid.org/0000-0001-9489-2342
Naglaa F El-SayedOrganometallic and Organometalloid Chemistry Department, National Research Centre 33ElBohouth St. (Former El Tahrir) Dokki 12622 Giza Egypt ewiesfawzy@yahoo.com ef.ewies@nrc.sci.eg.
Marwa El-HussienyOrganometallic and Organometalloid Chemistry Department, National Research Centre 33ElBohouth St. (Former El Tahrir) Dokki 12622 Giza Egypt ewiesfawzy@yahoo.com ef.ewies@nrc.sci.eg.
Shaimaa T MansourOrganometallic and Organometalloid Chemistry Department, National Research Centre 33ElBohouth St. (Former El Tahrir) Dokki 12622 Giza Egypt ewiesfawzy@yahoo.com ef.ewies@nrc.sci.eg.
Mohamed OthmanNormandie Univ., UNILEHAVRE, FR 3038 CNRS, URCOM 76600 Le Havre France.ORCID https://orcid.org/0000-0002-8379-5704
Marwa A FouadPharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University Kasr El-Aini St. Cairo 11562 Egypt.ORCID https://orcid.org/0000-0003-3227-8683
Huda R M RashdanChemistry of Natural and Microbial Products Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre 33 ElBohouth St. (Former El Tahrir) Dokki 12622 Giza Egypt.ORCID https://orcid.org/0000-0001-7474-1678
Ewies F EwiesOrganometallic and Organometalloid Chemistry Department, National Research Centre 33ElBohouth St. (Former El Tahrir) Dokki 12622 Giza Egypt ewiesfawzy@yahoo.com ef.ewies@nrc.sci.eg.ORCID https://orcid.org/0000-0002-4832-5766
Heba S A GharibBehaviour and Management of Animal, Poultry and Aquatics Department, Faculty of Veterinary Medicine, Zagazig University 44511 Zagazig Egypt.
Ghada H ElsayedHormones Department, Medical Research and Clinical Studies Institute, National Research Centre 33 El-Bohouth St., Dokki 12622 Giza Egypt ghadanrc@yahoo.com gh.hamdi@nrc.sci.eg.ORCID https://orcid.org/0000-0002-5505-217X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder characterized by progressive cognitive impairment and the accumulation of amyloid-β (Aβ) peptides. In this study, a novel series of triazole and phosphazine derivatives were synthesized and evaluated for neuroprotective activity in an aluminum chloride (AlCl

Identifiers

PMID41541199
PMCPMC12800931

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.