Evidence map›Paper›PMID 41541272›Full record

ArticleJournal of cancer science and clinical therapeutics2025

Predictive Genetic Testing in the Cancer Management and Prevention.

Niayesh Najafi, Kayvan Sasaninia, Zoya Najafi, Cady Babakhan Vartanian, Kevin Babakhan Vartanian, Faredun Dungore, Devendra K Agrawal

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cancer science and clinical therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Niayesh NajafiDepartment of Translational Research, College of the Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California, USA.
Kayvan SasaniniaDepartment of Translational Research, College of the Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California, USA.
Zoya NajafiDepartment of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Cady Babakhan VartanianBrainstim Centers, Calabasas, California.
Kevin Babakhan VartanianDepartment of Translational Research, College of the Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California, USA.
Faredun DungoreDepartment of Translational Research, College of the Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California, USA.
Devendra K AgrawalDepartment of Translational Research, College of the Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California, USA.

Funding

Research Education Program to Promote Diversity in Immunologic and Allergic DiseasesR25AI179582 · NIAID · WESTERN UNIVERSITY OF HEALTH SCIENCES · PI Devendra K. Agrawal · 2025 to 2026
$756k
NIAID NIH HHS R25 AI179582
6 · The paper itself

Abstract

Predictive genetic testing is a medical test that can effectively reduce morbidity and mortality caused by genetic diseases. This specific test predicts the risk of disease and provides prognostic information in asymptomatic persons, leading to the adoption of prevention strategies and individualized treatment in high-risk persons. Although the cause of some cancers is not known correctly, numerous studies establish that some specific gene mutations make people susceptible to specific cancer. Therefore, genetic screening of people, especially individuals with a family history of cancer, can be essential in reducing disease mortality and improving survival. Although genetic screening, in some cases, is associated with challenges, overall, it can be recognized as an important way to prevent and control hereditary diseases and save many lives. This article provides a critical review of the published reports and discusses the value of preventive genetic testing in preventing and controlling cancers and the role of hereditary mutations associated with cancer development.

Indexed as

Breast cancerCancer preventionColorectal cancerHereditary cancerOvarian cancerPancreatic cancerPersonalized medicinePredictive genetic testingProstate cancerScreening testUterine cancer

Identifiers

PMID41541272
PMCPMC12802875

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.