Evidence map›Paper›PMID 41542411›Full record

ArticlebioRxiv : the preprint server for biology2026

FUSION: A fast and uniform processing framework for whole-brain optical scattering tomography images.

Chong Chen, Peilin Gu, Martin Villiger, Néstor Uribe-Patarroyo, Brett Bouma, Jian Ren

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chong ChenDepartment of Radiology, Massachusetts General Hospital, Boston, MA 02129, USA.
Peilin GuDepartment of Radiology, Massachusetts General Hospital, Boston, MA 02129, USA.
Martin VilligerHarvard Medical School, Boston, MA 02115, USA.
Néstor Uribe-PatarroyoHarvard Medical School, Boston, MA 02115, USA.
Brett BoumaHarvard Medical School, Boston, MA 02115, USA.
Jian RenDepartment of Radiology, Massachusetts General Hospital, Boston, MA 02129, USA.ORCID 0000-0002-0511-7473

Funding

TRD3: Percutaneous and Interstitial ImagingP41EB015903 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Jacqueline Namati · 2012 to 2026
$22.4M
High-throughput optical investigation into intact large-scale nervous systems for Alzheimers diseaseR00AG059946 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI REN, JIAN · 2023 to 2025
$857k
NIA NIH HHS R00 AG059946NIBIB NIH HHS P41 EB015903
6 · The paper itself

Abstract

Coherent scattering imaging has seen substantial development in clinical ophthalmology and endoscopic microscopy owing to its high throughput, large dynamic range, and capability for label-free imaging. However, limited optical penetration has constrained its application to whole-organ imaging studies. Here, we propose a high-throughput coherent scattering imaging system assisted by tissue clearing, termed

Indexed as

Big dataset stitchingHight throughputIntact mouse brain imagingOptical coherent scattering imagingyTissue clearing

Identifiers

PMID41542411
PMCPMC12803274

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.