Evidence map›Paper›PMID 41542503›Full record

ArticlebioRxiv : the preprint server for biology2026

RNA Polymerase III subunit Polr3a is required for craniofacial cartilage and bone development.

Bailey T Lubash, Roxana Gutierrez, Kade Fink, Colette A Hopkins, Jessica C Nelson, Kristin E N Watt

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Bailey T Lubash
Roxana Gutierrez
Colette A HopkinsORCID 0000-0002-1206-455X

Funding

Understanding RNA Polymerase III transcription in neural crest cell and craniofacial developmentR00DE030971 · NIDCR · UNIVERSITY OF COLORADO DENVER · PI Kristin Emily Noack Watt · 2024 to 2026
$747k
NIDCR NIH HHS R00 DE030971
6 · The paper itself

Abstract

Transcription by RNA Polymerase III (Pol III) is essential for ribosome biogenesis and translation in all cells, but pathogenic variants in genes encoding subunits of Pol III lead to tissue-specific phenotypes including craniofacial differences. To understand the function of Pol III in craniofacial development, we examined

Identifiers

PMID41542503
PMCPMC12803176

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.