Evidence mapPaperPMID 41542809Full record

ReviewMolecular oncology2026

European Code Against Cancer, 5th edition - diet, excess body weight, physical activity, sedentary behavior, breastfeeding, and cancer.

Michael F Leitzmann, Ioanna Bakogianni, Annie S Anderson, Linda Bauld, Esteve Fernandez, Sherry Morris, Bernard Srour, Constantine Vardavas, Ioana Vlad, Sabine Vuik and 10 more

Abstract readReview
In one paragraph

Review in Molecular oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Michael F LeitzmannDepartment of Epidemiology and Preventive Medicine, University of Regensburg, Germany.ORCID 0000-0002-0371-2789
Ioanna BakogianniJoint Research Centre - European Commission, Ispra, Italy.
Annie S AndersonDivision of Population Health & Genomics, Ninewells Medical School, University of Dundee, Scotland.
Linda BauldUsher Institute and Behavioural Research UK, University of Edinburgh, Scotland.
Esteve FernandezTobacco Control Unit, WHO Collaborating Centre for Tobacco Control, Catalan Institute of Oncology (ICO), L'Hospitalet de Llobregat, Spain.
Sherry MorrisImperial College London, London, UK.
Bernard SrourUniversité Sorbonne Paris Nord and Université Paris Cité, INSERM, INRAE, CNAM, Center of Research in Epidemiology and StatisticS (CRESS), Nutritional Epidemiology Research Team (EREN), Bobigny, France.ORCID 0000-0002-1277-3380
Constantine VardavasDepartment of Hygiene, Epidemiology and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Greece.
Ioana VladDepartment of Policy and Public Affairs, World Cancer Research Fund International, London, UK.
Sabine VuikOrganisation for Economic Co-operation and Development, Paris, France.
Matty WeijenbergDepartment of Epidemiology, GROW Research Institute for Oncology and Reproduction, Maastricht University, The Netherlands.
Marta Roqué I FigulsInstitut de Recerca Sant Pau (IR SANT PAU), CIBERESP, Cochrane Iberoamérica, Barcelona, Spain.
David RigauInstitut de Recerca Sant Pau (IR SANT PAU), CIBERESP, Cochrane Iberoamérica, Barcelona, Spain.
Ariadna FeliuDepartment of Primary Care and Public Health, School of Public Health, Imperial College London, UK.ORCID 0000-0002-0033-9026
Hajo ZeebDepartment of Prevention and Evaluation, Leibniz - Institute for Prevention Research and Epidemiology - BIPS GmbH, Bremen, Germany.
Joachim SchüzEnvironmental and Lifestyle Epidemiology Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0001-9687-2134
Erica D'SouzaEnvironmental and Lifestyle Epidemiology Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0002-0744-665X
David RitchieEnvironmental and Lifestyle Epidemiology Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0003-4816-113X
Carolina EspinaEnvironmental and Lifestyle Epidemiology Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0001-6848-4687
Elio RiboliCancer Epidemiology and Prevention Research Unit, Imperial College London, UK.

Funding

EU4Health Programme - European Union 101075240World Health Organization 001
6 · The paper itself

Abstract

Diet, body weight, physical activity, sedentary behavior, and breastfeeding are modifiable factors influencing the cancer burden in the European Union, shaped by underlying social, commercial, environmental, and behavioral conditions. Excess body weight has reached epidemic levels, significantly influenced by widespread intake of sugar-sweetened beverages and ultra-processed foods rich in sugar, fat, and salt. Consumption of red and processed meat also commonly exceeds dietary recommendations. Physical inactivity and prolonged sedentary behavior are widespread. Breastfeeding rates vary widely across Europe but are generally low, particularly in high-income countries. To reduce cancer risk, the European Code Against Cancer, 5th edition (ECAC5) recommends a diet rich in whole grains, vegetables, legumes, and fruits, while limiting red meat and avoiding processed meat. Intake of vegetables, legumes, and fruits prevents aerodigestive tract cancers, while diets high in whole grains and low in red and processed meat reduce colorectal cancer risk. Avoiding excess body weight through diet and physical activity, and limiting prolonged sitting, decreases risk of numerous cancers. Promoting and supporting sustained breastfeeding contributes to lowering breast cancer risk. Key policy interventions, such as fiscal incentives, urban planning, marketing restrictions, and public awareness campaigns, are central to creating supportive environments for cancer prevention.

Indexed as

Body WeightBreast FeedingDietExerciseNeoplasmsSedentary BehaviorEuropeFemaleHumansbody weightbreastfeedingcancerdietEuropean Code Against Cancerphysical activitysedentary behavior

Identifiers

PMID41542809
PMCPMC12809479

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.