Evidence map›Paper›PMID 41543018›Full record

ArticleEuropean journal of neurology2026

The Use of Combined Fundus Photography and Perimetry for the Assessment of Patients Referred for Intracranial Hypertension or Follow-Up of the Diagnosis in a Tertiary Headache Center.

Zainab Rissan, Nadja Skadkær Hansen, Vlasta Vukovic-Cvetkovic, Louise Ninett Carlsen, Steffen Hamann, Marianne Wegener, Rigmor H Jensen, Henrik Winther Schytz

Abstract read
In one paragraph

Article in European journal of neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zainab RissanDepartment of Neurology, Danish Headache Center, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Nadja Skadkær HansenDepartment of Neurology, Danish Headache Center, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0002-5488-7992
Vlasta Vukovic-CvetkovicDepartment of Neurology, Danish Headache Center, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0003-4963-4541
Louise Ninett CarlsenDepartment of Neurology, Danish Headache Center, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0003-3634-7287
Steffen HamannDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-4318-2716
Marianne WegenerDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Rigmor H JensenDepartment of Neurology, Danish Headache Center, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0001-6433-5887
Henrik Winther SchytzDepartment of Neurology, Danish Headache Center, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0002-6262-2986

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIdiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure and papilledema. If left untreated, it can lead to vision loss, and, timely detection of papilledema is of paramount importance. Direct ophthalmoscopy can be difficult to perform and interpret for non-ophthalmologists. Therefore, this study aimed to investigate the impact of combined fundus photography and perimetry (CFPP) on patients with suspicion of new-onset IIH or IIH follow-up.

methodThe study was based on a cross-sectional, retrospective chart review of all patients who underwent CFPP examination due to suspicion of new-onset IIH or IIH follow-up at the Danish Headache Center between 2020 and 2023.

results258 patients were included for analysis, 92% females aged 17-72 years (mean age: 35.8 years). CFPP was performed due to clinical suspicion of new-onset IIH (38%), worsening/relapse of IIH (24%), assurance check in known IIH (19%), subjective symptoms (5%) or other reasons (14%). Overall, 62% had normal fundus photos, 21% had optic disc edema, 10% had other coincidental findings in the retina and/or optic disc, and 6% had an optic disc status unchanged from previous examinations. The use of CFPP confirmed the suspicion of IIH in 8% of patients and disproved it in 40% of patients. The CFPP results changed the treatment plan in 28% and caused referral to a neuroophthalmologist in 16% of patients.

conclusionCFPP can be used as a time- and resource-saving screening tool in headache patients with suspicion of new-onset IIH or follow-up in a tertiary neurology setting.

Indexed as

PapilledemaPhotographyPseudotumor CerebriVisual Field TestsAdolescentAdultAgedCross-Sectional StudiesFemaleFollow-Up StudiesFundus OculiHumansMaleMiddle AgedRetrospective StudiesTertiary Care Centers

Identifiers

PMID41543018
PMCPMC12809717

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.