Evidence map›Paper›PMID 41543266›Full record

ArticlemBio2026

Vitamin B12 promotes cefiderocol resistance and small-colony variants in carbapenem-resistant

Vyanka Mezcord, Irene Luu, Usman Akhar, German M Traglia, Cecilia Rodríguez, Samyar Moheb, Shayra D Sanchez, Maria T Soto, Maria J Cima Clave, Rodrigo Sieira and 8 more

Abstract read
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. New Insights intoPathogens (Basel, Switzerland) · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Vyanka Mezcord *Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA.
Irene Luu *Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA.
Usman AkharCenter for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA.
German M TragliaUnidad de Genómica y Bioinformática, Departamento de Ciencias Biológicas, CENUR Litoral Norte, Universidad de la República, Montevideo, Uruguay.
Cecilia RodríguezCenter for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA.
Samyar MohebCenter for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA.
Shayra D SanchezCenter for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA.
Maria T SotoLaboratorio Nacional/Regional de Referencia en Antimicrobianos, Instituto Nacional de Enfermedades Infecciosas, ANLIS Dr. Carlos G. Malbrán, Buenos Aires, Argentina.
Maria J Cima ClaveLaboratorio Nacional/Regional de Referencia en Antimicrobianos, Instituto Nacional de Enfermedades Infecciosas, ANLIS Dr. Carlos G. Malbrán, Buenos Aires, Argentina.
Rodrigo SieiraFundación Instituto Leloir-IIBBA CONICET, Buenos Aires, Argentina.
Marisel R TuttobeneCenter for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA.ORCID 0000-0003-0234-4643
Alejandra CorsoLaboratorio Nacional/Regional de Referencia en Antimicrobianos, Instituto Nacional de Enfermedades Infecciosas, ANLIS Dr. Carlos G. Malbrán, Buenos Aires, Argentina.
Marcelo E TolmaskyCenter for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA.ORCID 0000-0002-6298-7811
Robert A BonomoResearch Service and GRECC, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.ORCID 0000-0002-3299-894X
Luis A ActisDepartment of Microbiology, Miami University, Oxford, Ohio, USA.ORCID 0000-0001-9644-9088
Gauri RaoUniversity of Southern California, Los Angeles, California, USA.ORCID 0000-0002-8704-7770
Fernando PasteranLaboratorio Nacional/Regional de Referencia en Antimicrobianos, Instituto Nacional de Enfermedades Infecciosas, ANLIS Dr. Carlos G. Malbrán, Buenos Aires, Argentina.
Maria S RamirezCenter for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA.ORCID 0000-0002-9904-7890

Funding

Development of a broad spectrum teixobactin-lipopeptide hybrid for the treatment of lung infections caused by pan-drug resistant ‘superbugs’R01AI170889 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MALONEY, SARA ELIZABETH, RAO, GAURI G · 2022 to 2025
$3.8M
DEALING WITH ANTIBIOTIC RESISTANCE--ANTISENSE TECHNOLOGYR15AI047115 · NIAID · CALIFORNIA STATE UNIVERSITY FULLERTON · PI TOLMASKY, MARCELO E · 2000 to 2022
$1.8M
Identifying host human products responsible for natural transformation of resistance traits in Acinetobacter sppSC3GM125556 · NIGMS · CALIFORNIA STATE UNIVERSITY FULLERTON · PI RAMIREZ, MARIA SOLEDAD · 2018 to 2025
$851k
BLRD VA I01 BX001974NIAID NIH HHS R01 AI170889NIAID NIH HHS R15 AI047115NIGMS NIH HHS SC3 GM125556
6 · The paper itself

Abstract

Carbapenem-resistant

Indexed as

Acinetobacter baumanniiAnti-Bacterial AgentsCarbapenemsCephalosporinsVitamin B 12Bacterial ProteinsCefiderocolMicrobial Sensitivity TestsMolecular Docking SimulationAnti-Bacterial AgentsBacterial ProteinsCarbapenemsCefiderocolCephalosporinsVitamin B 12Acinetobacter baumanniiantibiotic resistancecefiderocolsmall-colony variantsTonB-dependent receptorsvitamin B12

Identifiers

PMID41543266
PMCPMC12892962

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.