Evidence map›Paper›PMID 41543644›Full record

ArticleMagma (New York, N.Y.)2026

Assessment of T

Viola Bader, Bernhard Strasser, Lukas Hingerl, Johannes J Kovarik, Sabina Frese, Lorenz Pfleger, Anna Duguid, Aaron Osburg, Martin Krššák, Thomas Scherer and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magma (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Viola BaderHigh-Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Bernhard StrasserHigh-Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Lukas HingerlHigh-Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Johannes J KovarikClinical Division of Internal Medicine III, Department of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria.
Sabina FreseHigh-Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Lorenz PflegerClinical Division of Internal Medicine III, Department of Endocrinology and Metabolism, Medical University of Vienna, Vienna, Austria.
Anna DuguidHigh-Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Aaron OsburgHigh-Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Martin KrššákClinical Division of Internal Medicine III, Department of Endocrinology and Metabolism, Medical University of Vienna, Vienna, Austria.
Thomas SchererClinical Division of Internal Medicine III, Department of Endocrinology and Metabolism, Medical University of Vienna, Vienna, Austria.
Wolfgang BognerHigh-Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Fabian NiessHigh-Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria. fabian.niess@meduniwien.ac.at.ORCID http://orcid.org/0000-0003-1235-7595

Funding

Novel 10.5 T deuterium-based MRS/I method to measure brain metabolismR01EB031787 · UNIVERSITY OF MINNESOTA · 2025 to 2025
$172k
Austrian Science Fund KLI 1106Austrian Science Fund WEAVE I 6037European Research Council 101088351National Institut of Health (NIH) R01EB031787
6 · The paper itself

Abstract

objectiveDeuterium metabolic imaging (DMI) is an emerging MR technique providing non-invasive insights into glucose metabolism. Reliable concentration estimation depends on knowledge of tissue specific relaxation times. This study reports T₁ and T₂ relaxation time constants of deuterium-labeled water (HDO) and glucose (Glc) from the human liver and kidney at 7T. MATERIALS AND

methodsTwelve healthy volunteers (6f/6 m) were examined using k-space-reordered inversion-recovery and spin-echo DMI with non-Cartesian concentric-ring trajectory (CRT) sampling. Seven volunteers underwent oral

resultsFaster longitudinal relaxation but similar transversal relaxation were observed for DISCUSSION: Hepatic and renal glucose homeostasis is often impaired in several pathophysiological conditions such as tumors, diabetes and metabolic dysfunction-associated steatotic liver disease. Using organ-specific

Indexed as

DeuteriumKidneyLiverMagnetic Resonance ImagingAdultDeuterium OxideFemaleGlucoseHealthy VolunteersHumansImaging, Three-DimensionalMaleMiddle AgedReproducibility of ResultsDeuteriumDeuterium OxideGlucose3D magnetic resonance imagingDeuterium metabolic imagingDMIGlucose metabolismRelaxation time measurements

Identifiers

PMID41543644
PMCPMC13354620

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.