Evidence map›Paper›PMID 41543801›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

Impact of exercise interventions on cardiorespiratory fitness in childhood cancer survivors: a systematic review and meta-analysis.

Nel Van Ermengem, Astrid Torrekens, Miek Hornikx, Deveny Vanrusselt, Anne Uyttebroeck, Véronique Cornelissen, Sabine Verschueren

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nel Van ErmengemDepartment of Rehabilitation Sciences, KU Leuven, Tervuursevest 101, 3001, Leuven, Belgium. nel.vanermengem@kuleuven.be.
Astrid TorrekensDepartment of Rehabilitation Sciences, KU Leuven, Tervuursevest 101, 3001, Leuven, Belgium.
Miek HornikxDepartment of Rehabilitation Sciences, KU Leuven, Tervuursevest 101, 3001, Leuven, Belgium.
Deveny VanrusseltDepartment of Oncology, KU Leuven, Leuven, Belgium.
Anne UyttebroeckDepartment of Oncology, KU Leuven, Leuven, Belgium.
Véronique CornelissenDepartment of Rehabilitation Sciences, KU Leuven, Tervuursevest 101, 3001, Leuven, Belgium.
Sabine VerschuerenDepartment of Rehabilitation Sciences, KU Leuven, Tervuursevest 101, 3001, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo summarize the impact of exercise interventions on cardiorespiratory fitness (CRF) in childhood cancer survivors (CCS) and determine optimal FITT (Frequency, Intensity, Type, Time) parameters to improve CRF in CCS.

methodsElectronic databases Medline, Embase, Web of Science, Scopus, Central, CINAHL, SPORTDiscus and clinicaltrials.gov were systematically searched from inception to 09/04/2025. Reference lists of relevant articles and review papers were manually screened. Studies included CCS < 19 years at diagnosis, undergoing any type of exercise intervention with peak oxygen consumption (VO

resultsTen studies involving 309 participants (55.7% male, 6-23 years) were included. Exercise interventions significantly improved VO

conclusionExercise interventions significantly improved CRF in CCS. Due to the limited amount and heterogeneity of included studies, optimal FITT parameters to increase CRF in CCS could not be identified. More randomized controlled trials with large sample sizes are needed to complement existing evidence and increase the robustness of the findings.

Indexed as

Cancer SurvivorsCardiorespiratory FitnessExercise TherapyNeoplasmsAdolescentChildHumansMaleOxygen ConsumptionWalk TestYoung AdultCardiorespiratory fitnessChildhood cancer survivorExerciseExercise interventionMeta-analysis

Identifiers

PMID41543801

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.