Evidence map›Paper›PMID 41545646›Full record

ArticleCommunications biology2026

The Neijiang pig T2T genome reveals domestication history and germplasm traits of Southwest Chinese local breeds.

Dong Chen, Shengdi Cui, Zhenjian Zhao, Pingxian Wu, Wenxuan Zhou, Patrick Kofi Makafui Tecku, Kai Wang, Junge Wang, Ziyang Chen, Shixin Yu and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Dong Chen *State Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, China.ORCID http://orcid.org/0009-0002-2031-8860
Shengdi Cui *State Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, China.ORCID http://orcid.org/0009-0009-1156-8228
Zhenjian ZhaoState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, China.ORCID http://orcid.org/0009-0001-1318-2398
Pingxian WuNational Center of Technology Innovation for Pigs, Chongqing, China.ORCID http://orcid.org/0000-0002-6098-9549
Wenxuan ZhouState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, China.ORCID http://orcid.org/0009-0003-9665-928X
Patrick Kofi Makafui TeckuState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, China.ORCID http://orcid.org/0000-0003-0987-3118
Kai WangSichuan New Hope Liuhe Pig Breeding Technology Co. Ltd, Chengdu, Sichuan, China.ORCID http://orcid.org/0000-0002-7151-4362
Junge WangState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, China.ORCID http://orcid.org/0009-0001-3653-5424
Ziyang ChenState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, China.ORCID http://orcid.org/0009-0005-7114-345X
Shixin YuState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, China.ORCID http://orcid.org/0009-0008-9194-4491
Jiamiao ChenState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, China.ORCID http://orcid.org/0009-0007-3646-5626
Yaoxi ZhouState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, China.ORCID http://orcid.org/0009-0003-8618-2756
Runjie HuangState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, China.ORCID http://orcid.org/0009-0009-3820-3771
Xuewei LiState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, China.ORCID http://orcid.org/0000-0003-4560-5137
Guoqing TangState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, China. tyq003@163.com.ORCID http://orcid.org/0000-0002-6920-5050

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A complete telomere-to-telomere (T2T) pig genome serves as a high-precision reference for functional genomics and structural variation studies due to its high level of completeness and minimal error rate. Here we present a comprehensive framework for genomic research aimed at the effective utilization of Neijiang pig genetic resources. The highly repetitive centromeric regions of the Neijiang pig are identified, and their characteristic centromeric landscapes are constructed using chromosomal landmark identification combined with centromeric repeat monomer localization strategies. Genome-wide association studies (GWAS) based on the T2T reference genome identify key genetic loci associated with reproductive traits, offering potential molecular targets for genetic improvement. Gene family analysis and genetic investigation into head morphology in Neijiang pigs reveal selection signals within olfactory receptor (OR) genes that are associated with head shape differentiation, highlighting the potential role of environmental adaptation in the phenotypic domestication of Chinese indigenous pig breeds. The Neijiang pig T2T genome (NJP-T2T) assembly provides a critical reference resource and foundational dataset for genetic improvement and functional genomic studies in indigenous pig breeds.

Indexed as

DomesticationGenomeSus scrofaAnimalsBreedingChinaGenome-Wide Association StudyGenomicsPhenotypeSwine

Identifiers

PMID41545646
PMCPMC12920665

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.