ArticleObesity surgery2026
Bariatric Surgery and Renal Function: A Mid-Term Prospective Analysis of Estimated Glomerular Filtration Rate Dynamics in Adults with and without Diabetes Mellitus.
Article in Obesity surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundObesity is associated with a range of medical problems, including impaired renal function. Type 2 diabetes mellitus (T2DM), independently, exerts a direct and multifactorial impact on renal health. This study evaluates and compares the effects of metabolic bariatric surgery (MBS) on renal function in patients with and without T2DM.
methodsThis prospective cohort study followed patients undergoing MBS over three years, stratified by T2DM status. Participants were matched using propensity scores (PS), and postoperative trajectories of creatinine-based estimated glomerular filtration rate (eGFR) were compared. Generalized estimating equation (GEE) method was employed to identify factors significantly associated with changes in eGFR over time.
resultsA total of 1895 participants (83% women), including 770 PS-matched individuals, were enrolled in the study. All participants had a baseline eGFR ≥ 60 mL/min/1.73m
conclusionRenal function improved following MBS, regardless of T2DM status. Furthermore, older age, being a woman, higher baseline eGFR, and undergoing SG were associated with less eGFR improvements.
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