ReviewCancer cell international2026
Tissue-derived extracellular vesicles: comparing Ts-EVs and Te-EVs in extraction, characteristics and research trends.
Review in Cancer cell international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Extracellular vesicles (EVs) are lipid bilayer-enclosed nanovesicles that mediate intercellular communication by transferring bioactive molecules such as proteins, lipids, and nucleic acids. Tissue-derived EVs (Ti-EVs) have gained increasing attention due to their ability to reflect the physiological or pathological state of the tissue microenvironment. Ti-EVs are generally classified into two types: tissue-sourced EVs (Ts-EVs) and tissue-explant-derived EVs (Te-EVs). Although both types originate from tissues, they differ in isolation methods, biological characteristics, and research applications. This review systematically compares the isolation procedures, methodological advantages and limitations, and research progress of Ts-EVs and Te-EVs. Furthermore, we summarize their applications across various organ systems, focusing on their protein and RNA cargo. Finally, we discuss current challenges and future directions in Ti-EVs research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.