Evidence map›Paper›PMID 41546002›Full record

ArticleBMC ophthalmology2026

Vitreous chamber depth as part of axial elongation in pediatric myopia.

Sinan Liu, Ming Li, Yihua Zhu, Huihang Wang

Abstract read
In one paragraph

Article in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sinan Liu *Department of Ophthalmology, The First Affiliated Hospital, Fujian Medical University, No.20 Cha Zhong Road, Fuzhou, 350005, China.
Ming Li *School of Smart Marine Science and Engineering, Fujian University of Technology, Fuzhou, China.
Yihua ZhuDepartment of Ophthalmology, The First Affiliated Hospital, Fujian Medical University, No.20 Cha Zhong Road, Fuzhou, 350005, China. zhuyihua889@163.com.
Huihang WangDepartment of Ophthalmology, The First Affiliated Hospital, Fujian Medical University, No.20 Cha Zhong Road, Fuzhou, 350005, China. 870416538@qq.com.

Funding

National Natural Science Foundation of China 82270179the Joint Funding Project of Science and Technology Innovation of Fujian Provincial Department of Science and Technology 2024Y9132the project of Fujian Provincial Clinical Medical Research Center of Eye Diseases and Optometry YK-YJZX
6 · The paper itself

Abstract

backgroundThis study explored the connections between axial length (AL) and other ocular parameters, including central corneal thickness (CCT), aqueous chamber depth (AD), lens thickness (LT), and vitreous chamber depth (VCD), during myopia progression in children.

methodsThis study was conducted on a Chinese pediatric population, comprising 42 participants in a prospective cohort and 406 participants in a retrospective study. Standardized protocols were used to measure ocular parameters. Statistical analyses included descriptive statistics, t-tests, ANOVA, and correlation analyses to compare parameters across AL subgroups.

resultsSignificant positive proportional relationships were observed between AL and VCD (R² = 0.97), and moderate correlations with AD (R² = 0.49) and LT (R² = 0.30). No significant correlation was found between AL and CCT (R² = 0.00). Longer AL was associated with increased VCD and AD and a decrease in LT. Regular monitoring of AL, and particularly VCD, provides a sensitive measure of ongoing myopia progression and can be used to track its dynamics.

conclusionsVCD is the primary component associated with AL elongation in pediatric myopia, with minimal contributions from AD and LT. Regular monitoring of AL and VCD may improve the assessment of myopia progression and support personalized intervention strategies.

Indexed as

Axial Length, EyeMyopiaVitreous BodyAdolescentChildCorneaDisease ProgressionFemaleHumansLens, CrystallineMaleProspective StudiesRetrospective StudiesAxial lengthMyopia progressionPediatric ophthalmologyVitreous chamber depth

Identifiers

PMID41546002
PMCPMC12896177

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.