Evidence map›Paper›PMID 41546793›Full record

ArticleSleep & breathing = Schlaf & Atmung2026

Changes in the apnea index to hypopnea index ratio after upper airway stimulation therapy.

E Kant, J A Hardeman, R J Stokroos, M P Copper

Abstract read
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

E KantDepartment of Otorhinolaryngology, Head and Neck Surgery, Sint Antonius Hospital, Nieuwegein, The Netherlands. e.kant@umcutrecht.nl.ORCID 0000-0002-8433-8660
J A HardemanDepartment of Pulmonology, Sint Antonius Hospital, Nieuwegein, The Netherlands.ORCID 0009-0002-0685-0981
R J StokroosDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.ORCID 0000-0001-8037-2573
M P CopperDepartment of Otorhinolaryngology, Head and Neck Surgery, Sint Antonius Hospital, Nieuwegein, The Netherlands.ORCID 0000-0002-6021-2262

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo examine the impact of upper airway stimulation therapy on the apnea index/hypopnea index ratio in patients with obstructive sleep apnea.

methodsWe retrospectively analyzed 118 patients who received an upper airway stimulation device between 2015 and 2022.

resultsThe apnea–hypopnea index at baseline was 35.3 ± 8.9 events/hour, which significantly decreased to 14.9 ± 13.1 events/hour at three months and 14.9 ± 9.9 events/hour at twelve months (p < 0.001). The apnea index/hypopnea index ratio shifted from 1:1.3 at baseline to 1:2.3 and 1:2.4 at three and twelve months, respectively, indicating a greater reduction in apneas compared to hypopneas (p < 0.001).

conclusionThese findings suggest that upper airway stimulation therapy causes a shift from apneas to hypopneas, which may indicate that therapy prevents complete upper airway obstructions but may not fully prevent partial obstructions. These findings emphasize to look beyond overall apnea–hypopnea index reduction when evaluating the treatment effect of upper airway stimulation therapy.

Indexed as

Electric Stimulation TherapySleep Apnea, ObstructiveAdultAgedFemaleHumansMaleMiddle AgedPolysomnographyRetrospective StudiesTreatment OutcomeAI/HI ratioOSAPhenotypesUASUpper airway stimulation

Identifiers

PMID41546793
PMCPMC12812074

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.