Evidence map›Paper›PMID 41547737›Full record

ArticleBMC pulmonary medicine2026

Association between lipid accumulation product and asthma in US adults: evidence from the NHANES 2005-2020.

Cuiyun Tao, Ye Liang, Junguo Li, Xiuzhang Zhai, Cuizhen Long, Jianghui Zeng

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Article in BMC pulmonary medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Cuiyun TaoDepartment of Clinical Laboratory, The Second Nanning People's Hospital, The Third Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Ye LiangDepartment of Hematology, The Second Nanning People's Hospital, The Third Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Junguo LiDepartment of Clinical Laboratory, The Second Nanning People's Hospital, The Third Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Xiuzhang ZhaiDepartment of Clinical Laboratory, The Second Nanning People's Hospital, The Third Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Cuizhen LongDepartment of Clinical Laboratory, The Second Nanning People's Hospital, The Third Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Jianghui ZengDepartment of Clinical Laboratory, The Second Nanning People's Hospital, The Third Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China. qt000184@sr.gxmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity has been recognized as a risk factor for both the onset and progression of asthma. The lipid accumulation product (LAP) is considered a reliable surrogate marker for visceral adiposity and its related metabolic complications. This study aimed to investigate the potential association between LAP and asthma in adults.

methodsData were obtained from the National Health and Nutrition Examination Survey (NHANES) spanning 2005 to March 2020. Multivariable logistic regression, smooth curve fitting, threshold effect analysis and subgroup analyses were conducted to evaluate the association between LAP and asthma in adults. In addition, sensitivity analyses were performed to assess the stability.

resultsWithin the sample of 16,861 participants, 1,432 (8.5%) were diagnosed with current asthma. After full adjustment, each one-unit increase in ln LAP was associated with 39% higher odds of asthma prevalence. Compared with those in the lowest quartile (Q1), participants in the highest quartile (Q4) of ln LAP had a 65% increase in the odds of asthma (OR = 1.65, 95% CI: 1.15-2.38). In addition, gender difference and diabetes status altered the association between LAP and asthma (P for interaction < 0.05).

conclusionsThis study highlights a significant association between LAP and asthma prevalence in adults, particularly among females and individuals with diabetes.

Indexed as

AsthmaLipid Accumulation ProductObesityAdultCross-Sectional StudiesFemaleHumansLogistic ModelsMaleMiddle AgedNutrition SurveysPrevalenceRisk FactorsUnited StatesAsthmaLipid accumulation productNHANESObesity

Identifiers

PMID41547737
PMCPMC12896105

What Socratic holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.