Evidence map›Paper›PMID 41549156›Full record

ArticleNeurochemical research2026

Serum Aberrant Expression of miR-431-5p and Their Diagnostic Value in Parkinson's Disease.

Chang Liu, Jin Xu, Shuangfa Mao, Pengjie Li, Fangfang Lai, Peng Chen

Abstract read
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In one paragraph

Article in Neurochemical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chang Liu *Department of Neurosurgery, Zigong First People's Hospital, No. 42 Shangyihao 1st Branch Road, Wuxing Street, Ziliujing District, Zigong, Sichuan, China. Liuchang_ZG@163.com.
Jin Xu *School of Clinical Medical Technology, Sichuan Vocational College of Health and Rehabilitation, Zigong, Sichuan, China.
Shuangfa MaoSchool of Basic Medical Sciences, Sichuan Vocational College of Health and Rehabilitation, Zigong, Sichuan, China.
Pengjie LiSchool of Rehabilitation, Sichuan Vocational College of Health and Rehabilitation, Zigong, Sichuan, China.
Fangfang LaiSchool of Clinical Medical Technology, Sichuan Vocational College of Health and Rehabilitation, Zigong, Sichuan, China.
Peng ChenDepartment of Neurosurgery, The First Affiliated Hospital of USTC, Hefei, Anhui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-coding RNA plays an important role in the occurrence and development of Parkinson's disease (PD). This study only explores the diagnostic value of miR-431-5p in PD and its role in the development of PD. A total of 92 patients with PD were selected as the PD group, and 100 healthy individuals undergoing physical examinations were selected as the control group. The levels of serum miR-431-5p were detected by reverse transcription quantitative polymerase chain reaction (RT-qPCR). The receiver operating characteristic (ROC) curve was drawn to evaluate the diagnostic value of serum miR-431-5p for PD. Multivariate Logistic regression was utilized to analyze the risk factors of PD with cognitive impairment. The in vitro PD cell model was constructed by inducing SH-SY5Y cells with MPP

Indexed as

MicroRNAsParkinson DiseaseAgedApoptosisAutophagyBiomarkersCell Line, TumorCell ProliferationFemaleHumansMaleMiddle AgedOxidative StressBiomarkersMicroRNAsMIRN431 microRNA, humanAutophagyDiagnostic biomarkersMiR-431-5pParkinson’s disease

Identifiers

PMID41549156

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.