ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026
Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance.
Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Plant pathogens pose a significant threat to global food security by causing up to 80% agricultural yield losses. Nucleotide-binding, leucine-rich repeat immune receptors (NLRs) were widely proved to protect plants from a wide array of pathogens evasion. Recent studies have shown significant progress in bioengineering NLRs to enhance plant immunity through improved pathogen recognition, investigation of immune evasion, and structural insights into NLR functions. However, bioengineering NLRs for enhanced plant immunity faces key challenges of maintaining specificity, addressing pathogen evolution, and minimizing autoactivity risks. Here, we synthesize recent advances in understanding NLR biology and highlight key bioengineering strategies, including mismatched pairs, domain swapping, and targeted mutagenesis, that leverage this knowledge to enhance disease resistance. The successful applications of NLRs precision editing strategies have also been demonstrated to improve resistance in various plants, showcasing their overall effectiveness. This review highlights promising avenues to strengthen plant immunity against pathogens, which have enormous potential for application in agriculture and breeding techniques.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.