Evidence map›Paper›PMID 41549301›Full record

ReviewStem cell research & therapy2026

Stem cells in organogenesis and regeneration.

Tasmia Jahin Mim, Iftakhar Ahmad, Salima Raiyan Basher, Md Foyzur Rahman, Sandeep Reddy Ambati, Kiranmai Venkatagiri, Nimrah Seher, Dinesh Kumar, Neeraj Choudhary, Suresh Babu Kondaveeti

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Stem cell research & therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tasmia Jahin MimDepartment of Mathematics and Natural Sciences, BRAC University, Dhaka, Bangladesh.
Iftakhar AhmadDepartment of Zoology, Comilla Victoria Government College, National University of Bangladesh, Gazipur, Bangladesh.
Salima Raiyan BasherDepartment of Biochemistry and Molecular Biology, University of Dhaka, Dhaka, Bangladesh.
Md Foyzur RahmanDepartment of Pharmacy, Dhaka International University, Dhaka, Bangladesh.
Sandeep Reddy AmbatiDepartment of Pharmacy Practice, Santhiram College of Pharmacy, Nandyal, Andhra Pradesh, India.
Kiranmai VenkatagiriDepartment of Pharmacy Practice, Santhiram College of Pharmacy, Nandyal, Andhra Pradesh, India.
Nimrah SeherDepartment of Biochemistry, University of Agriculture Faisalabad, Faisalabad, Pakistan.
Dinesh KumarGNA School of Pharmacy, GNA University, Phagwara, Punjab, India. dineshpotlia123@gmail.com.
Neeraj ChoudharyGNA School of Pharmacy, GNA University, Phagwara, Punjab, India. dr.neerajchoudhary@gmail.com.
Suresh Babu KondaveetiSymbiosis Medical College for Women & Symbiosis University Hospital and Research Centre, Symbiosis International (Deemed University), Pune, 412115, India. ksuresh.babu@smcw.siu.edu.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stem cells are the basis of organogenesis and regeneration, providing cellular support during the development, maintenance, and repair of tissues. This review provides a brief overview of the major stem cell types and their sources, as well as the key stages of organogenesis that depend on stem cell activity. This review highlights critical signalling pathways, including Wnt, Notch, Hedgehog, and BMP. These pathways regulate the fate and lineage specification of stem cells. The review identifies the roles of embryonic stem cells and induced pluripotent stem cells in organ formation as well as the newly arising methods for directed differentiation. Mesenchymal stem cells play a crucial role in tissue regeneration and therapeutic repair. Organoids are potent experimental models for studying development and disease. The impact of stem cell niches and microenvironmental regulation is discussed, along with the cellular and molecular processes that underlie recovery after damage. The review encompasses the translational progress of stem-cell-based therapies, current clinical trials, and the challenges in safety and efficacy. Moreover, the review also explores the introduction of advanced technologies, such as CRISPR, 3D bioprinting, and synthetic biology, as well as theoretical considerations, including future directions and ethical issues. Together, these insights provide a comprehensive overview of stem cell biology and highlight their potential for clinical translation.

Indexed as

OrganogenesisRegenerationStem CellsAnimalsCell DifferentiationEmbryonic Stem CellsHumansSignal Transduction3D bioprintingCRISPREmbryonic stem cellsOrganogenesisRegenerationStem cellsSynthetic biology

Identifiers

PMID41549301
PMCPMC12896028

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.