Evidence map›Paper›PMID 41549480›Full record

ArticleJournal of pediatric gastroenterology and nutrition2026

Effect of cow's milk protein allergy during infancy on eating behavior at 4 years of age: A cohort study.

Anne Jardim-Botelho, Marcela Barros Barbosa de Oliveira, Jackeline Motta-Franco, Tatiane Graça Martins, Sarah Cristina Fontes Vieira, Ikaro Daniel de Carvalho Barreto, Aline Vieira Bezerra, Ricardo Queiroz Gurgel

Abstract read
In one paragraph

Article in Journal of pediatric gastroenterology and nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anne Jardim-BotelhoFederal University of Sergipe, Aracaju, Brazil.ORCID https://orcid.org/0000-0002-2459-4574
Marcela Barros Barbosa de OliveiraFederal University of Sergipe, Aracaju, Brazil.
Jackeline Motta-FrancoFederal University of Sergipe, Aracaju, Brazil.
Tatiane Graça MartinsFederal University of Sergipe, Aracaju, Brazil.
Sarah Cristina Fontes VieiraPediatrics of Federal University of Sergipe, São Cristóvão, Brazil.
Ikaro Daniel de Carvalho BarretoCentro Brasileiro de Pesquisa em Avaliação e Seleção e de Promoção de Eventos (Brazilian Center for Research in Assessment, Selection, and Event Promotion - CEBRASPE, Brasília, Brazil.
Aline Vieira BezerraUniversidade Tiradentes (Tiradentes University), Aracaju, Brazil.
Ricardo Queiroz GurgelFederal University of Sergipe, Aracaju, Brazil.

Funding

Foundation for the Support of Research and Technological Innovation of the State of Sergipe - FAPITEC/SE, BrazilResearch for Brazil's Unified Health System Program - SUS-PPSUS 06/2018
6 · The paper itself

Abstract

objectivesThis study aimed to investigate the eating behaviors of preschool children who had been exposed to a restricted diet due to an oral food challenge-confirmed diagnosis of cow's milk protein allergy (CMPA) during early infancy.

methodsThis prospective cohort study compared the eating behaviors of Brazilian children previously diagnosed with CMPA to those of a nonallergic control group. Baseline data on infant feeding, clinical history, and sociodemographic characteristics were collected and later analyzed in association with the Children's eating behavior questionnaire (CEBQ) at 4 years of age. Linear regression models were used to assess associations between CMPA and CEBQ scores, with both crude and adjusted analyses performed.

resultsA total of 74 children, with a mean age of 3.2 months at recruitment, were enrolled (30 with CMPA and 44 controls). Cesarean section delivery, rural geographic location, early introduction of substitute infant formula, and a family history of atopy were associated with higher food fussiness scores. After adjusting for early predictors of eating behaviors, the CMPA group scored significantly higher on the "desire to drink" scale (B adjusted: 2.61; p = 0.031) and on the "food fussiness" scale (B adjusted: 4.07; p = 0.017).

conclusionsAdherence to a CME diet during infancy, following an OFC-confirmed CMPA diagnosis, was found to have a long-term impact on eating behavior, as evidenced by higher scores on food fussiness and desire to drink scales, which are linked to feeding difficulties.

Indexed as

Feeding BehaviorMilk HypersensitivityMilk ProteinsAnimalsBrazilCase-Control StudiesChild, PreschoolCohort StudiesFemaleFood FussinessHumansInfantMaleProspective StudiesSurveys and QuestionnairesMilk Proteinschildren's eating behavior questionnairefeeding difficultyfood fussinessinfant feeding

Identifiers

PMID41549480
PMCPMC13050815

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.