Evidence map›Paper›PMID 41550076›Full record

ArticleAnnals of medicine2026

Preoperative neutrophil-to-lymphocyte ratio and refracture risk in hip fracture patients: a propensity score-matched analysis.

Rui La, Qian Wu, Rui Xu, Fanqi Kong, Zhongtai Zhang, Wenquan Ding, Zhiyuan He, Qingfeng Ding, Haiyue Zu, Hongxia Zhu and 4 more

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Article in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Rui LaDepartment of Orthopedic Surgery, Orthopedic Institute, The First Affiliated Hospital, Soochow University, Suzhou, China.
Qian WuDepartment of Orthopedic Surgery, Orthopedic Institute, The First Affiliated Hospital, Soochow University, Suzhou, China.
Rui XuDepartment of Information, The First Affiliated Hospital of Soochow University, Suzhou, China.
Fanqi KongDepartment of Orthopedic Surgery, Orthopedic Institute, The First Affiliated Hospital, Soochow University, Suzhou, China.
Zhongtai ZhangDepartment of Orthopedic Surgery, Orthopedic Institute, The First Affiliated Hospital, Soochow University, Suzhou, China.
Wenquan DingDepartment of Orthopedic Surgery, Orthopedic Institute, The First Affiliated Hospital, Soochow University, Suzhou, China.
Zhiyuan HeDepartment of Orthopedic Surgery, Orthopedic Institute, The First Affiliated Hospital, Soochow University, Suzhou, China.
Qingfeng DingDepartment of Orthopedic Surgery, Orthopedic Institute, The First Affiliated Hospital, Soochow University, Suzhou, China.
Haiyue ZuDepartment of Orthopedic Surgery, Orthopedic Institute, The First Affiliated Hospital, Soochow University, Suzhou, China.
Hongxia ZhuDepartment of Nursing, The First Affiliated Hospital of Soochow University, Suzhou, China.
Lixin HuangDepartment of Orthopedic Surgery, Orthopedic Institute, The First Affiliated Hospital, Soochow University, Suzhou, China.
Wu XuDepartment of Orthopedic Surgery, Orthopedic Institute, The First Affiliated Hospital, Soochow University, Suzhou, China.
Zhigang ZhangDepartment of Orthopedic Surgery, Orthopedic Institute, The First Affiliated Hospital, Soochow University, Suzhou, China.
Shenghao WangDepartment of Orthopedic Surgery, Orthopedic Institute, The First Affiliated Hospital, Soochow University, Suzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relationship between preoperative neutrophil-to-lymphocyte ratio (NLR) and refracture risk in hip fracture patients remains unclear.

methodsThis retrospective study included 701 patients with hip fractures between 2018 and 2020. Multivariate logistic regression and propensity score matching (PSM) assessed the association between preoperative NLR (analysed as a continuous variable) and refracture risk, adjusting for age, sex, comorbidities, fracture characteristics and laboratory parameters. Subgroup and dose-response analyses evaluated robustness.

resultsRefracture occurred in 119 patients (16.98%). Each unit increase in NLR (as a continuous variable) was associated with 8.0% increased refracture odds (odds ratio (OR) = 1.080, 95% confidence interval (CI) = 1.019-1.144,

conclusionsElevated preoperative NLR independently predicts refracture risk in hip fracture patients. This readily available biomarker may facilitate risk stratification and guide prevention strategies.

Indexed as

Hip FracturesLymphocytesNeutrophilsAgedAged, 80 and overBiomarkersFemaleHumansLogistic ModelsLymphocyte CountMalePreoperative PeriodPropensity ScoreRecurrenceRetrospective StudiesRisk AssessmentBiomarkership fracturesNeutrophil–lymphocyte ratiopropensity scorerefracture

Identifiers

PMID41550076
PMCPMC12818325

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.